Ischemic stroke and infection: A brief update on mechanisms and potential therapies

DP Ghelani, HA Kim, SR Zhang, GR Drummond… - Biochemical …, 2021 - Elsevier
… to spontaneous bacterial infections [18]. As mentioned, stroke-induced immunosuppression
is probably mediated … of T cell subpopulations promoted by bacterial metabolites, consistent …

Stroke-induced immunosuppression: implications for the prevention and prediction of post-stroke infections

J Faura, A Bustamante, F Miró-Mur… - Journal of …, 2021 - Springer
… developed more spontaneous bacterial lung infections than WT … increased the NK-cell-mediated
immune response against post-… This, in turn, could be promoting the appearance of …

Stroke-induced immunosuppression and poststroke infection

K Shi, K Wood, FD Shi, X Wang, Q Liu - Stroke and vascular neurology, 2018 - svn.bmj.com
… . Stroke-induced immunodeficiency promotes spontaneous bacterial infections and is
mediated by sympathetic activation reversal by poststroke T helper cell type 1-like …

Ischemic stroke alters immune cell niche and chemokine profile in mice independent of spontaneous bacterial infection

BY Farris, KL Monaghan, W Zheng… - Immunity …, 2019 - Wiley Online Library
… -mediated aspiration following stroke is the sole cause of SAP. However, it is now clear that
the stroke-induced immunosuppression … CCL22 is known to promote Th2-mediated immune …

Immunodepression, infections, and functional outcome in ischemic stroke

WF Westendorp, C Dames, PJ Nederkoorn, A Meisel - Stroke, 2022 - Am Heart Assoc
… Besides dysphagia, stroke-induced immunodepression is … impairs the antibacterial defense
mediated by Th1 cytokines, such … Activation of this nucleus, in turn, promotes glucocorticoid …

Ischemia, immunosuppression and infection—tackling the predicaments of post-stroke complications

R Shim, CHY Wong - International journal of molecular sciences, 2016 - mdpi.com
… brain promotes mitochondrial-mediated production … Stroke-induced immunosuppression
is now more universally acknowledged to be the main explanation for susceptibility to infection

Research progress in stroke-induced immunodepression syndrome (SIDS) and stroke-associated pneumonia (SAP)

DD Liu, SF Chu, C Chen, PF Yang, NH Chen… - Neurochemistry …, 2018 - Elsevier
… Inflammatory reactions after stroke promote tissue healing … of immune cell differentiation,
immunodeficiency diseases, oncology and … Stroke-induced activation of iNKT cells mediates an …

Immunomodulation after ischemic stroke: potential mechanisms and implications for therapy

C Santos Samary, P Pelosi, P Leme Silva… - Critical Care, 2016 - Springer
… of ischemic stroke-induced immunosuppression and stroke-… induces systemic
immunosuppression mediated by several … -associated pneumonia but promote further collateral …

Neuroinflammation and peripheral immunity: Focus on ischemic stroke

H Wang, S Zhang, L Xie, Z Zhong, F Yan - International …, 2023 - Elsevier
… and stroke-induced immunosuppression in the context of IS. … pro-inflammatory type M1,
promote the secretion of a variety of … (PVN) in tMCAO rats is likely mediated by glutamate via the …

CD200-CD200R1 inhibitory signaling prevents spontaneous bacterial infection and promotes resolution of neuroinflammation and recovery after stroke

RM Ritzel, A Al Mamun, J Crapser, R Verma… - Journal of …, 2019 - Springer
… followed by a state of profound immunosuppression [12]. This … activation and amelioration
of stroke-induced lymphopenia. … -mediated susceptibility to spontaneous bacterial infection