… The structural basis of the regulation of serotonin (5-hydroxytryptamine, 5-HT) receptors by
… addresses this issue by resolving five structures of 5-HT 1 receptor–G protein complexes. …

… variety of functions displayed by serotonin receptors, is regulated by … structures of serotonin
receptors obtained using crystallography and cryo-electron microscopy. Capturing structures …

… 5-HT receptors have high levels of basal activity and are subject to regulation by lipids, but
the structural basis for the lipid regulation and basal activation of these receptors and the pan-…

… serotonin receptors’ structure based on available studies. It will discuss the structural
characteristics of different serotonin receptor … in their conformation when the receptors are …

… Here, the search for the structural determinants of selectivity between selected serotonin
receptor subtypes was carried out. Special attention was focused on 5-HT 7 R and the cross-…

… structure of an antibody selectively bound to the extracellular surface of a GPCR, shedding
light on the structural basis of receptor recognition… for studying receptor localization, structure, …

… and compared it with the 5-HT 1B /ERG structure. These crystal structures provide a
comprehensive structural basis for understanding the receptor–ligand interactions of the 5-HT family …

… structures of the full-length mouse 5-HT 3 receptor in complex with the anti-emetic drug
tropisetron, with serotonin, and with serotonin … The tropisetron-bound structure resembles those …

… structures of the serotonin 2B receptor, suggesting that this binding mode could be a general
feature of the serotonin receptor … the CRAC motifs in the serotonin 1A receptor. Our results …

… structure reveals the recognition mechanism of 5-HT 5A by 5-CT and adds to the pool of
the structures for deepening our understanding of the ligand-binding mode of 5-HT receptors. …