Structural deficits in salience network regions are associated with increased impulsivity and compulsivity in alcohol dependence
EN Grodin, CR Cortes, PA Spagnolo… - Drug and alcohol …, 2017 - Elsevier
Background Convergent preclinical and clinical evidence has linked the anterior insula to
impulsivity and alcohol-associated compulsivity. The anterior insula is functionally
connected to the anterior cingulate cortex, together comprising the major nodes of the
salience network, which serves to signal salient events, including negative consequences.
Clinical studies have found structural and functional alterations in the anterior insula and
anterior cingulate cortices of alcohol dependent individuals. No studies have yet …
impulsivity and alcohol-associated compulsivity. The anterior insula is functionally
connected to the anterior cingulate cortex, together comprising the major nodes of the
salience network, which serves to signal salient events, including negative consequences.
Clinical studies have found structural and functional alterations in the anterior insula and
anterior cingulate cortices of alcohol dependent individuals. No studies have yet …
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