New perspectives of physiological and pathological functions of nucleolin (NCL)

W Jia, Z Yao, J Zhao, Q Guan, L Gao - Life sciences, 2017 - Elsevier
… In this review, we present an overview on the structure, localizations and various functions
of NCL, and further describe how the multiple functions of NCL are correlated to its multiple …

Multifaceted nucleolin protein and its molecular partners in oncogenesis

I Ugrinova, M Petrova, M Chalabi-Dchar… - … chemistry and structural …, 2018 - Elsevier
… In this review, we will describe the different functions of nucleolin in oncogenesis through its
functions of nucleolin in oncogenesis through the interaction of nucleolin with other proteins. …

Nucleolin and nucleophosmin: nucleolar proteins with multiple functions in DNA repair

DD Scott, M Oeffinger - Biochemistry and cell biology, 2016 - cdnsciencepub.com
… The highly abundant proteins nucleophosmin (NPM1) and nucleolin (NCL) are two such
factors … the structure and regulation of NPM1 and NCL and will briefly introduce their functions

[HTML][HTML] Roles of nucleolin: Focus on cancer and anti-cancer therapy

Z Chen, XH Xu - Saudi medical journal, 2016 - ncbi.nlm.nih.gov
… Thus, nucleolin may be a novel and promising target for anti-cancer treatment. Here, we
describe how nucleolin act functions in cancer development and describe nucleolin-dependent …

Nucleolin: a cell portal for viruses, bacteria, and toxins

F Tonello, ML Massimino, C Peggion - Cellular and Molecular Life …, 2022 - Springer
… characteristics that make nucleolin able to … nucleolin ability to interact with nucleic acids,
with proteins, but also with carbohydrates and lipids. This modular multivalence allows nucleolin

Nuclear functions of nucleolin through global proteomics and interactomic approaches

A Salvetti, Y Couté, A Epstein, L Arata… - Journal of proteome …, 2016 - ACS Publications
Nucleolin (NCL) is a major component of the cell nucleolus, which has the ability to rapidly
shuttle to several other cells’ compartments. NCL plays important roles in a variety of …

[PDF][PDF] Nucleolin: role in bacterial and viral infections

MT Malik - EC Microbiology, 2018 - researchgate.net
… The structure of nucleolin The human nucleolin gene is comprised of 14 exons with 13 …
of the nucleolin gene encodes a small nucleolar RNA, termed U20. Human nucleolin has a …

The nucleolus: structure and function

ML Dubois, FM Boisvert - The Functional Nucleus, 2016 - Springer
… are B23, fibrillarin and Nucleolin. The B23 protein acts in several functions associated with
the … Nucleolin has been involved in the regulation of gene expression, chromatin remodeling, …

Nucleolin acts as the receptor for C1QTNF4 and supports C1QTNF4-mediated innate immunity modulation

SK Vester, RL Beavil, S Lynham, AJ Beavil… - Journal of Biological …, 2021 - ASBMB
nucleolin is mediated by the second C1q-like domain of C1QTNF4 and the C terminus of
nucleolin… Our results suggest that nucleolin may serve as a docking molecule for C1QTNF4 and …

Nucleolar protein nucleolin functions in replication stress–induced DNA damage responses

K Kawamura, F Qi, Q Meng, I Hayashi… - Journal of radiation …, 2019 - academic.oup.com
… that nucleolin plays an important role in IR-induced DSB damage responses [10]. We showed
that nucleolin … Furthermore, our results revealed that this functional activity of nucleolin was …