… (Top left) Schematic overview of the lymph node anatomy … shows a B cell transporting an
antigen–immune complex to the … on subcapsular sinus macrophages (SSMs) in the subcapsular …

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… body that are responsible for transporting lymph, which contains … B cells and follicular dendritic
cells (FDCs), known as B cell … afferent lymphatic vessels, travels through the subcapsular …

… transport of immune complexes by lymph node B cells. … Immune complex relay by
subcapsular sinus macrophages and noncognate B cells drives antibody affinity maturation. …

… the transport of antigens from lymph into lymph node follicles… of immune complex (IC)
presentation by SSMs to B cells. … by SSMs and B cells in the immune synapse. These changes …

… To obtain the best experience, we recommend you use a more up … seen to transport antigen,
we assumed that memory B cell … after injecting AlexFluo488 labeled immune complex at 8 d …

… transgenic B cell tolerance to H-2K antigens encountered in … While non-cognate B cells that
capture immune complexes from … by lymph node-resident cDC in the subcapsular sinus and …

… ) to flow through the lymph node from the subcapsular sinus [17, … the lymph node increases
the pool of T and B cells inside the … antigen in the form of immune complexes, which they bind …

… DC-mediated antigen transport and T cell activation have … dynamics of B cell activation in
lymph nodes, although similar … In the subcapsular sinus: antigen encounter and early B cell …

… separated compartments: the subcapsular sinus (SSC), the … them in a complement-dependent
manner to follicular B cells … IL-6 following immune complex stimulation also contributes …