… Therefore, we searched the methylation on the amino acid residues known as substrates
as well as the possible ones. Using Mascot ion score >35 and peptide length between 7 and …

… compare specific activities. However, the specific activities of the mammalian DNA methylase
… an intrinsic property of eukaryotic DNA methylases, whether the substrate DNA used is not …

… methionine (AdoMet) and the DNA substrate, and for catalysis. C… prokaryotic and eukaryotic
C5 DNA methyltransferases and … along the substrate and catalysis of successive methylation …

… if these enzymes of the same DNA substrate specificity somehow differ in mechanisms of …
Similar observation was made in the case of eukaryotic DNMT1 39 , where ssDNA substrate …

… To explore the sensitivity of DpnI to different methylation status, we synthesized single-stranded
DNA probes with or without 6mA at specific sequence motifs, and annealed them to …

… activity on preferred substrates in vitro revealed … DNA methylation marks with specific histone
modifications, we performed chromatin immunoprecipitation followed by deep sequencing (…

… evolved to increase tRNA substrate specificity and prevent rampant non-specific methylation.
… Eukaryotic two-subunit dependent methyltransferases. The figure shows examples of …

… such protein-DNA interactions as specific lac repressor binding … for eukaryotic cells to
modulate specific protein-DNA in… if DNA methylation is an ordered bi-substrate reaction in …

… Thus, m 6 A marks in eukaryotic DNA and RNA might be … by RM systems is methylation of
specific bases in DNA, recent … oxidation capacity in vitro on DNA substrates 54. However, all …

… methyltransferase, activity is highest when the substrate … [ 20 ] However, specific enzymes
with a role in the reversal of … polymerases and some eukaryotic DNA polymerases. [ 108, 109 ] …