Subversion of Innate Phagocytic Cells by Orientia tsutsugamushi

CK Min, NH Cho - Autophagy: Cancer, Other Pathologies, Inflammation …, 2016 - Elsevier
… Inflammatory responses mediated by specific cytokines and chemokines generated by
infected host cells are potentially associated with antibacterial immunity or with immunological …

Gene expression and involvement of signaling pathways during host–pathogen interplay in Orientia tsutsugamushi infection

S Panda, SK Swain, BP Sahu, R Sarangi - 3 Biotech, 2022 - Springer
… Before the bacterium infects a new host cell, the host cell membrane encapsulates budding
… the increased in Orientia tsutsugamushi induced TNF-α and Ca2 + signaling activity. Ca2 + …

An update on host-pathogen interplay and modulation of immune responses during Orientia tsutsugamushi infection

FE Díaz, K Abarca, AM Kalergis - Clinical microbiology reviews, 2018 - Am Soc Microbiol
… antigen presentation (85, 88), the extent and mechanisms of autophagy subversion should
be … genome also harbors a high number of genes encoding host cell interaction and signaling

[HTML][HTML] Orientia tsutsugamushi: The dangerous yet neglected foe from the East

A Banerjee, S Kulkarni - International Journal of Medical Microbiology, 2021 - Elsevier
… is not known, the host cellular components and their related … by the bacteria to enter the host
cells as confirmed by the OT-… be traced back to autophagy subversion. Thus, knowledge of …

Orientia tsutsugamushi: A neglected but fascinating obligate intracellular bacterial pathogen

J Salje - PLoS pathogens, 2017 - journals.plos.org
… Budding out of host cells Intracellular pathogens typically exit infected host cells by host
cell lysis (eg, Chlamydia spp., Plasmodium falciparum), extrusion or expulsion of a bacteria-…

Orientia tsutsugamushi: An Unusual Intracellular Bacteria—Adaptation Strategies, Available Antibiotics, and Alternatives for Treatment

P Srivastava, A Shukla, R Singh, R Kant, N Mishra… - Current …, 2024 - Springer
… by host immune system and replicate inside host cell to increase their number causing
severity of disease [8]. After invasion, host cells … However, each host cell has a limited carrying …

Orientia tsutsugamushi Modulates Endoplasmic Reticulum Stress to Benefit its Intracellular Growth and Targets NLRC5 to Inhibit Major Histocompatibility Complex I …

KG Rodino - 2018 - scholarscompass.vcu.edu
tsutsugamushi to the host cell surface and subsequent signaling for actin rearrangement.The
bacterial ligand(s) that participates in this interaction has not been identified.Fibronectin is …

[图书][B] Orientia tsutsugamushi Secretes Two Ankyrin Repeat-Containing Effectors aia a Type 1 Secretion System to Inhibit Host NF-κB Function

S Evans - 2017 - search.proquest.com
… ) into the host cell to modulate host cell processes. The O. tsutsugamushi genome encodes
one … Subversion of host cell signaling by Orientia tsutsugamushi. Microbes Infect 13, 638-48 (…

Orientia tsutsugamushi OtDUB is expressed and interacts with adaptor protein complexes during infection

HE Adcox, JM Berk, M Hochstrasser… - Infection and …, 2022 - Am Soc Microbiol
… as an obligate endosymbiont that replicates to high numbers in the cytoplasm of
arthropod and mammalian host cells indicates that it effectively interfaces with eukaryotic …

[PDF][PDF] Elucidation of Mechanisms of Host Immunity against Orientia tsutsugamushi in a Newly Developed Murine Model

G Xu - 2017 - utmb-ir.tdl.org
… Scrub typhus, caused by a Gram-negative obligately intracellular coccobacillus, Orientia
tsutsugamushi, is a long neglected but important tropical disease. Orientia tsutsugamushi