… as well as at the merozoite apex and surface, are the major focus of this thesis. PfEMP1 is
the major surface antigen and mediates rosetting (binding of parasitized RBCs (pRBCs) to two …

… variant surface antigen Plasmodium falciparum erythrocyte membrane protein-1 (PfEMP1). …
transcription due to contact with Plasmodium falciparum infected red blood cells. Our results …

… surface as well as at the merozoite apex and surface, are the major focus of this thesis.
PfEMP1 is the major surface antigen … of parasitized RBCs (pRBCs) to two or more RBCs), a …

… These mechanisms are mediated by the interaction between variant surface antigens (…
PfEMP1, RIFIN, and STEVOR have been shown to mediate rosetting, the potential co-expression …

… , an individual PfEMP1 may also contain different adhesive domains with different receptor
… blood cell suggest that they are involved in antigenic variation as PfEMP1 [226]. This was …

… C PfEMP1 antigens, and IgG to group A PfEMP1 therefore … in areas with natural transmission
of P. falciparum parasites (12, … the surface of IEs in a mutually exclusive manner (only one …

… immunization with DBLβ_motif antigens induces cross-… single- and dual-peptide antisera
yielded immunofluorescence patterns typical of IgG reacting with IE surface-expressed PfEMP1 …

… protein 1 (PfEMP1) family has been clearly associated with antigenic variation and … by
individual parasites through the expression of a single or several different PfEMP1 on the surface …

… ~60 different PfEMP1 variants of which only one is expressed … Plasmodium falciparum-infectederythrocyte
surface antigens … Surface Co-Expression of Two Different PfEMP1 Antigens on …

… In Plasmodium falciparum, the parasite responsible for the most severe form of human
malaria, three major variant surface antigen families – PfEMP1… of Plasmodium falciparum-infected …