Survival of patients with multiple intracranial metastases treated with stereotactic radiosurgery: does the number of tumors matter?

MA Knoll, EK Oermann, AI Yang, I Paydar… - American journal of …, 2018 - journals.lww.com
Background: Defining prognostic factors is a crucial initial step for determining the
management of patients with brain metastases. Randomized trials assessing radiosurgery
have commonly limited inclusion criteria to 1 to 4 brain metastases, in part due to multiple
retrospective studies reporting on the number of brain metastases as a prognostic indicator.
The present study reports on the survival of patients with 1 to 4 versus≥ 5 brain metastases
treated with radiosurgery. Methods: We evaluated a retrospective multi-institutional …
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