[HTML][HTML] Neovascularization of engineered tissues for clinical translation: Where we are, where we should be?

MA Nazeer, IC Karaoglu, O Ozer, C Albayrak… - APL …, 2021 - pubs.aip.org
… If critical GFs such as vascular endothelial growth factor (VEGF… In in vitro pre-vascularization,
ECs are seeded into scaffolds … a sustained manner using purpose-built biomaterial scaffolds

[HTML][HTML] A bilayer vascular scaffold with spatially controlled release of growth factors to enhance in situ rapid endothelialization and smooth muscle regeneration

Y Wang, T Wu, J Zhang, Z Feng, M Yin, X Mo - Materials & Design, 2021 - Elsevier
… with uniform heparin and vascular endothelial growth factors (… to provide sufficient support
to maintain the vascular structure [15,… and vascularization of small diameter vascular grafts …

… release in vivo of vascular endothelial growth factor within a subcutaneous scaffolded islet implant reduces early islet necrosis and improves performance of the graft

JA Gebe, A Preisinger, MD Gooden… - Cell …, 2018 - journals.sagepub.com
… A central cavity in the scaffold holds a 2-mm diameter … and temperature 30 —a sufficient
duration of release that could, in … time span of VEGF release), vascularization of the implants was …

Strategies for re-vascularization and promotion of angiogenesis in trauma and disease

RC Gonçalves, A Banfi, MB Oliveira, JF Mano - Biomaterials, 2021 - Elsevier
… factor (FGF) family, vascular endothelial growth factor (VEGF) or … protein delivery, by
maintaining the expression of the target … in scaffolds that resemble the native microvascular …

Repairing peripheral nerve defects with revascularized tissue‐engineered nerve based on a vascular endothelial growth factor‐heparin sustained release system

Z Bin, Z Zhihu, M Jianxiong… - Journal of tissue …, 2020 - Wiley Online Library
… Therefore, we believe that early vascularization of grafts plays an important role in the survival
… The sustained-release VEGF acellular nerve scaffold was prepared by using heparin as a …

Strategies to promote vascularization in 3D printed tissue scaffolds: trends and challenges

A Joshi, S Choudhury, SB Gugulothu… - …, 2022 - ACS Publications
… The rapid release of AP and sustained release of OP resulted in vascularized bone
regeneration upon implantation (Figure 2C). Other approaches include utilizing small bioactive …

Vascular endothelial growth factor immobilized on mussel-inspired three-dimensional bilayered scaffold for artificial vascular graft application: In vitro and in vivo …

SJ Lee, ME Kim, H Nah, JM Seok, MH Jeong… - Journal of colloid and …, 2019 - Elsevier
vascular scaffolds, there has still been only limited development of scaffold materials possessing
both sufficient … molecules for promotion of endothelial cell (EC) vascularization and is a …

[HTML][HTML] Promoting early neovascularization of SIS-repaired abdominal wall by controlled release of bioactive VEGF

R Tang, X Wang, H Zhang, X Liang, X Feng, X Zhu… - RSC …, 2018 - pubs.rsc.org
… (DNPs) loaded with vascular endothelial growth factor 165 (… the scaffold-induced endogenous
regeneration through rapid … Our results proved that sufficient early neovascularization

Polydopamine-modified konjac glucomannan scaffold with sustained release of vascular endothelial growth factor to promote angiogenesis

X Zhu, S Wu, K Yang, W Wei, Y Aziz, W Yuan… - International Journal of …, 2024 - Elsevier
… can induce continuous vascularization via the prolonged phosphorylation of VEGF
receptors. However, blood vessels that formed under the high doses of VEGF might result in …

Multifunctional fibrous scaffolds for bone regeneration with enhanced vascularization

C Wang, WW Lu, M Wang - Journal of materials chemistry B, 2020 - pubs.rsc.org
… Therefore, vascular endothelial growth factor (VEGF), an … factors in scaffolds and administrating
their release profiles following a … scaffolds had a synergistic effect (sustained rhBMP-2 …