Mitochondrial aspects of synaptic dysfunction in Alzheimer's disease
Q Cai, P Tammineni - Journal of Alzheimer's disease, 2017 - content.iospress.com
… with non-synaptic mitochondria. This study suggests that synaptic mitochondria are more …
-induced damage and synaptic mitochondrial stress is an early pathological alteration in AD…
-induced damage and synaptic mitochondrial stress is an early pathological alteration in AD…
[HTML][HTML] Synapse pathology in Alzheimer's disease
J Griffiths, SGN Grant - Seminars in Cell & Developmental Biology, 2023 - Elsevier
… glial cells, mitochondrial dysfunction, and the link with AD risk genes. We consider the
emerging view that synapse pathology may operate at a further level, that of synapse diversity, …
emerging view that synapse pathology may operate at a further level, that of synapse diversity, …
Synaptic basis of Alzheimer's disease: Focus on synaptic amyloid beta, P-tau and mitochondria
A John, PH Reddy - Ageing research reviews, 2021 - Elsevier
… the disease and serve as markers and therapeutic targets. This article addresses the
mechanisms of synaptic action, mitochondrial regulation/dysregulation, resulting synaptic changes …
mechanisms of synaptic action, mitochondrial regulation/dysregulation, resulting synaptic changes …
Defective mitophagy and synaptic degeneration in Alzheimer's disease: Focus on aging, mitochondria and synapse
H Morton, S Kshirsagar, E Orlov, LE Bunquin… - … Radical Biology and …, 2021 - Elsevier
… -related oxidative stress, and mitochondrial dysfunction. It is generally accepted … at synapses
and synaptic mitochondria interfere with synaptic activities, including the release of synaptic …
and synaptic mitochondria interfere with synaptic activities, including the release of synaptic …
Mitochondrial dysfunction and synaptic transmission failure in Alzheimer's disease
L Guo, J Tian, H Du - Journal of Alzheimer's Disease, 2017 - content.iospress.com
… for the protection of synaptic activity and the subsequentcognitive function. … mitochondrial
pathology in AD and discuss the link between mitochondrial dysfunction and chemical synaptic …
pathology in AD and discuss the link between mitochondrial dysfunction and chemical synaptic …
Synaptic mitochondria: an early target of amyloid-β and tau in Alzheimer's disease
AK Torres, C Jara, HS Park-Kang… - … of Alzheimer's …, 2021 - content.iospress.com
… in mitochondria and triggers dysfunction. Finally, we discuss that synaptic mitochondrial …
Therefore, synaptic mitochondrial dysfunction could be a predisposing factor for AD or an …
Therefore, synaptic mitochondrial dysfunction could be a predisposing factor for AD or an …
[HTML][HTML] Region-specific depletion of synaptic mitochondria in the brains of patients with Alzheimer's disease
EK Pickett, J Rose, C McCrory, CA McKenzie… - Acta …, 2018 - Springer
… we observe abnormal mitochondrial morphology in synapses in AD … synaptic mitochondria
are affected in a region-specific manner in Alzheimer’s disease, which may impair synaptic …
are affected in a region-specific manner in Alzheimer’s disease, which may impair synaptic …
Understanding the neuronal synapse and challenges associated with the mitochondrial dysfunction in mild cognitive impairment and Alzheimer's disease
H Verma, P Gangwar, A Yadav, B Yadav, R Rao… - Mitochondrion, 2023 - Elsevier
… by synaptic degradation. This review summarizes the challenges associated with the
synaptic mitochondrial … in restoring the synaptic activity and rendering neuroprotection in AD. …
synaptic mitochondrial … in restoring the synaptic activity and rendering neuroprotection in AD. …
[HTML][HTML] Dysfunctional mitochondrial bioenergetics and synaptic degeneration in Alzheimer disease
J Tang, A Oliveros, MH Jang - International neurourology journal, 2019 - ncbi.nlm.nih.gov
… associated with synaptic lesions and … synaptic mitochondria pathology involves dysfunctional
trafficking of this organelle, to maladaptive epigenetic contributions affecting mitochondrial …
trafficking of this organelle, to maladaptive epigenetic contributions affecting mitochondrial …
The role of mitochondrial dysfunction in Alzheimer's disease pathogenesis
T Ashleigh, RH Swerdlow, MF Beal - Alzheimer's & Dementia, 2023 - Wiley Online Library
… classical AD pathology and … mitochondria to further contribute to disease progression,
but we do not conclude that these are the drivers of AD or the primary cause of neuronal/synaptic …
but we do not conclude that these are the drivers of AD or the primary cause of neuronal/synaptic …
相关搜索
- alzheimer's disease mitochondrial dysfunction
- alzheimer's disease amyloid β
- alzheimer's disease amyloid beta
- alzheimer disease synaptic degeneration
- alzheimer's disease mouse model
- alzheimer's disease defective autophagy and mitophagy
- mitochondrial dynamics in alzheimer's disease
- alzheimer's disease mitochondrial cascade hypothesis
- synapse loss in alzheimer's disease
- mitochondria in alzheimer's disease key role
- alzheimer's disease and diabetes mitochondrial perturbation
- alzheimer's disease brain damaged mitochondria
- alzheimer's disease oxidative stress
- models of alzheimer's disease tau pathology
- alzheimer's disease synaptic transmission failure
- synaptic dysfunction in alzheimer's disease