… with non-synaptic mitochondria. This study suggests that synaptic mitochondria are more …
-induced damage and synaptic mitochondrial stress is an early pathological alteration in AD…

… glial cells, mitochondrial dysfunction, and the link with AD risk genes. We consider the
emerging view that synapse pathology may operate at a further level, that of synapse diversity, …

… the disease and serve as markers and therapeutic targets. This article addresses the
mechanisms of synaptic action, mitochondrial regulation/dysregulation, resulting synaptic changes …

… -related oxidative stress, and mitochondrial dysfunction. It is generally accepted … at synapses
and synaptic mitochondria interfere with synaptic activities, including the release of synaptic …

… for the protection of synaptic activity and the subsequentcognitive function. … mitochondrial
pathology in AD and discuss the link between mitochondrial dysfunction and chemical synaptic …

… in mitochondria and triggers dysfunction. Finally, we discuss that synaptic mitochondrial …
Therefore, synaptic mitochondrial dysfunction could be a predisposing factor for AD or an …

… we observe abnormal mitochondrial morphology in synapses in AD … synaptic mitochondria
are affected in a region-specific manner in Alzheimer’s disease, which may impair synaptic …

… by synaptic degradation. This review summarizes the challenges associated with the
synaptic mitochondrial … in restoring the synaptic activity and rendering neuroprotection in AD. …

… associated with synaptic lesions and … synaptic mitochondria pathology involves dysfunctional
trafficking of this organelle, to maladaptive epigenetic contributions affecting mitochondrial …

… classical AD pathology and … mitochondria to further contribute to disease progression,
but we do not conclude that these are the drivers of AD or the primary cause of neuronal/synaptic …