Interactive associations of vascular risk and β-amyloid burden with cognitive decline in clinically normal elderly individuals: findings from the Harvard Aging Brain …

JS Rabin, AP Schultz, T Hedden, A Viswanathan… - JAMA …, 2018 - jamanetwork.com
cognitive decline, both alone and synergistically with … measure thought to reflect small
vessel ischemic changes) and/or … Possible synergistic effects were tested in a separate model …

Synergistic effects of longitudinal amyloid and vascular changes on lobar microbleeds

YJ Kim, HJ Kim, JH Park, S Kim, SY Woo, KC Kwak… - Neurology, 2016 - AAN Enterprises
… of interstitial fluid and solutes, including β-amyloid, from the brain. … without dementia and
ischemic stroke patients. Our … lobar CMBs and cognitive impairment in svMCI patients. The …

The impact of amyloid-β or tau on cognitive change in the presence of severe cerebrovascular disease

H Jang, HJ Kim, YS Choe, SJ Kim… - Journal of …, 2020 - content.iospress.com
… CSVD burden had synergistic effects on cognitive decline, while this interaction effect was
… study findings as SVCI patients in this study had very severe ischemia on MRI. Nevertheless…

[HTML][HTML] Independent effect of Aβ burden on cognitive impairment in patients with small subcortical infarction

SH Kang, M Kang, JH Han, ES Lee, KJ Lee… - Alzheimer's Research & …, 2023 - Springer
… [5], and Aβ deposition and cSVD burden have synergistic effects on cognitive decline.
The mechanism of PSCI may differ from by ischemic stroke subtype (territorial, lacunar, or …

Brain amyloid β, cerebral small vessel disease, and cognition: A memory clinic study

FN Saridin, S Hilal, SG Villaraza, A Reilhac… - Neurology, 2020 - AAN Enterprises
… processes with a possible synergistic effect between Aβ and … and a wide spectrum of
cognitive impairment. We aimed to … , WMH represents cerebral ischemia related to small vessel …

[HTML][HTML] Synergistic interaction of high blood pressure and cerebral beta-amyloid on tau pathology

T Kim, D Yi, MS Byun, H Ahn, JH Jung, N Kong… - Alzheimer's research & …, 2022 - Springer
… between high BP and cerebral β-amyloid (Aβ) deposition in … from diagnosis of mild cognitive
impairment or dementia; they … mediate the synergistic effect of high BP on tau pathology. …

Dopaminergic depletion, βamyloid burden, and cognition in Lewy body disease

HS Yoo, S Lee, SJ Chung, YH Lee, PH Lee… - Annals of …, 2020 - Wiley Online Library
β-amyloid, tau, and α-synuclein had synergistic interactions leading to the acceleration of
cognitive decline… Taken together, our results suggest that occipital β-amyloid burden interacts …

[HTML][HTML] Contributions of vascular burden and amyloid abnormality to cognitive decline in memory clinic patients

V van Gils, I Ramakers, WJ Jansen… - Journal of …, 2023 - content.iospress.com
… The total count of cortical and subcortical microbleeds, ischemic strategic and non-strategic …
We only showed a synergistic effect of vascular disease and amyloid abnormality on verbal …

[HTML][HTML] Increased cerebral blood volume in small arterial vessels is a correlate of amyloid-β–related cognitive decline

J Hua, SW Lee, NIS Blair, M Wyss, JMG Van Bergen… - Neurobiology of …, 2019 - Elsevier
… and follow-up CBVa in several brain regions synergistically predicted cognitive decline over
2 … regression shows synergistic effects from GM CBVa and β-amyloid on cognitive decline in …

Obstructive sleep apnea and hypertension with longitudinal amyloid-β burden and cognitive changes

OM Bubu, SS Kaur, AK Mbah… - American journal of …, 2022 - atsjournals.org
… the synergistic associations of co-occurring OSA and HTN on Aβ concentrations and cognitive
decline in … Overall, our findings highlight the importance of examining synergistic effects of …