… , DOPA-melanin through the polymerization of dihydroxyindole (… Camacho are Cryptococcus
neoformans (top left) and C. … neoformans requires exogenous precursors for the synthesis …

… of tissue and that melanin pigment synthesized in vivo is … as a polymerization precursor is
capable of producing melanin … display reduced virulence in mice and decreased melanization …

… We will particularly focus on Cryptococcus neoformans and … oxidized and polymerized to
produce DOPA melanin [8]. … Melanin synthesis needs to occur in a contained environment …

… all animal kingdoms and is also the type of melanin synthesized by C. … -DHN, which is
subsequently polymerized to become DHN melanin, the sole end … neoformans in infected rodents. …

… of fungal biosynthesis for the three most prevalent melanin … by the oxidation and subsequent
polymerization of HGA, an … Meanwhile, infections with Cryptococcus neoformans or C. …

… METH-treated mice infected with … neoformans melanin is synthesized by a single
copper-dependent laccase enzyme encoded by the LAC1 gene through the oxidative polymerization …

… Melanins are natural pigments synthesized by members of all biological kingdoms by
polymerizing phenolic and/or indolic compounds, resulting in negatively charged, hydrophobic …

… , we prepared India ink suspensions of mouse lung homogenates from mice infected with …
is comprised predominantly of GXM that is synthesized intracellularly and exported in secretory …

… intermediates produced during melanin biosynthesis [13], and … , the protein that catalyses
melanin polymerization. There was … of Cryptococcus neoformans and prolongs survival of mice …

… They are formed by the oxidative polymerization of phenolic or indolic compounds. In fungi,
… several animal-pathogenic fungi, like Aspergillus fumigatus or Cryptococcus neoformans (23…