… , known as melanin, by oxidative polymerization of phenolic … that resembles mammalian
melanin biosynthesis [11–13]. … This effect was observed for Cryptococcus neoformans, whose …

… melanin production has been eliminated are avirulent in mice… is followed by polymerization
to yield the melanin pigments23,… However, our findings suggest that melanin biosynthesis in C…

… of fungal biosynthesis for the three most prevalent melanin … by the oxidation and subsequent
polymerization of HGA, an … Meanwhile, infections with Cryptococcus neoformans or C. …

… caused by Cryptococcus neoformans, an encapsulated yeast that has been a major public
… the chitin synthesis process. Naturally, chitin synthases (CHS), which polymerizes GlcNAc …

… Fungal pathogens of the Cryptococcus neoformans species complex (C. … It is highly probable
that the in vivo synthesis of the melanin pigment arises from the polymerization of a diverse …

… genes associated with biosynthesis and/or the regulation of capsule or melanin were determined.
… neoformans in mice [84]. Mutants in this gene also present defects in mating, growth at …

… due to longer surviving period of the inoculated mice [87]. … While melanin production is a cell
surface synthesis, the … to pigmented compound, melanin, via auto-polymerization of quinine-…

… protective immunity to Cryptococcal infection in mice through … Melanin synthesis though this
pathway begins with the union … ) glucan affects Cryptococcus neoformans from ultrastructure …

… molecules similar to those polymerized into the chitin layer … During infection, cryptococcal
melanin is synthesized from … neoformans survive better than mice infected with the wild …

… Phagocytosis blocking has been observed by melanized Cryptococcus neoformans and …
Synthesis of polymerized melanin by Cryptococcus neoformans in infected rodents. …