… Antimicrobial/ antiproliferative activities were tested against eight … -chalcone derivatives were
investigated in the MCF-7 breast … the antiproliferative effects of these coumarinyl chalcones …

… Docking study was performed for the evaluation of the anticancer activity of synthesized
derivatives 3a-m against tyrosine kinase protein (4csv) using VLife MDS software. The ligands …

… Other chalcones that exhibit antiproliferative activity in cancer cells are isoliquiritigenin and
2′-O-methyl isoliquiritigenin [13]. In this context, natural products have relatively high safety …

… when chalcone 3 was treated with hydrazine in boiling dioxane, chromenodiazepine derivative
9 was obtained instead of 3-coumarinyl… In contrast, hydrazinolysis of chalcone 3 in glacial …

… synthesized a series of coumarinyl chalcone hybrids bearing different substitutions at ring B
of chalcone… and were characterized for anti-proliferative activity against breast cancer MCF-7 …

… -chalcone hybrids 3a and 3b were utilized as versatile precursor for the synthesis of
coumarinyl-pyridine and coumarinyl… Hepatocellular Carcinoma (HepG2) and breast cancer …

… The chalcone derivative 3 [32] was synthesized through a … -coumarinyl pyridine-3-carbonitrile
12 revealed moderate effects … performed for the anti-proliferative activity against MCF-7 …

… [83] reported the antiproliferative activity of coumarinyl chalcones against breast cancer cell
lines. … at 2,3,4 carbons of “B” ring of chalcone proved to be potent antiproliferative agents. …

… including coumarin–chalcone compounds were synthesized, and using the … -2K in breast
cancer cells at submicromolar concentrations (<1 μM) and showed significant antiproliferative …

… were selected and further tested on HeLa, MRC-5, and MCF-7 (breast carcinoma) cell
lines. The examined compounds exhibit strong in vitro anticancer activities with moderate-to-high …