Synthesis and antitumor activity of some new pyrazolo [1, 5-a] pyrimidines

AS Hassan, MF Mady, HM Awad, TS Hafez - Chinese Chemical Letters, 2017 - Elsevier
… approach for the preparation of a new series of pyrazolo[1,5-a]pyrimidine derivatives 7a–i,
11a–c and their relevant Schiff bases 13a–c. All the newly synthesized compounds were …

An insight on synthetic and medicinal aspects of pyrazolo [1, 5-a] pyrimidine scaffold

S Cherukupalli, R Karpoormath… - European journal of …, 2017 - Elsevier
… These numerous synthetic pathways have prompted medicinal scientists to discover several
new drugs consisting of pyrazolo[1,5-a]pyrimidines as a core moiety. These are also known …

Synthesis, In Vitro Antimicrobial and Cytotoxic Activities of Some New Pyrazolo[1,5-a]pyrimidine Derivatives

AM Fouda, HAS Abbas, EH Ahmed, AA Shati, MY Alfaifi… - Molecules, 2019 - mdpi.com
synthesis of several poly substituted fused pyrazolopyrimidines. Pyrazolo[1,5-a]pyrimidines
Symmetrical 3,6-diarylazo-2,5,7-triaminopyrazolo[1,5-a]pyrimidine (8a,b) were synthesized

Synthesis and biological evaluation of pyrazolo[1,5-a]pyrimidine-3-carboxamide as antimicrobial agents

AS Hassan, DM Masoud, FM Sroor… - Medicinal Chemistry …, 2017 - Springer
… In summary, we have synthesized a novel series of pyrazolo[1,5-a]pyrimidines 5a–d, 10a–f, …
1a, b with 1-aryl-3-(dimethylamino)prop-2-en-1-ones 2a, b, (arylidene)malononitriles 6a–c or …

Synthesis of new sulfapyrimidine and pyrazolo[1,5-a]pyrimidine derivatives

EA Ahmed, GH Elgemeie, RA Azzam - Synthetic Communications, 2023 - Taylor & Francis
… In summary, this study introduces a new derivatives of pyrimidine compounds, including
sulfapyrimidines and pyrazolo[1,5-a]pyrimidines. It was described the reaction of sulfa …

Synthesis and in-vitro anti-proliferative evaluation of some pyrazolo [1, 5-a] pyrimidines as novel larotrectinib analogs

MH Attia, EZ Elrazaz, SZ El-Emam, AT Taher… - Bioorganic …, 2020 - Elsevier
… substrates in the synthesis of several biologically active heterocyclic compounds and drug
intermediates, were chosen in this study for the synthesis of pyrazolo[1,5-a]pyrimidines 11a–j. …

Useful Precursors for Synthesis of Some New Azolo[3,4‐d]pyridiazines, Azolo[1,5‐a]pyrimidines, Azolo[5,1c]triazines, Pyrazoles, and Benzo[b][l,4]diazepine

AO Abdelhamid, AA Fahmi… - Journal of Heterocyclic …, 2016 - Wiley Online Library
Pyrazolo[l,5-a]pyrimidines, … synthesis of a variety of heterocyclic systems for biological
evaluation 31-35, we report herein the synthesis of some new Azolo[3,4-d]pyridazines, Azolo[1,5-a]…

[HTML][HTML] Synthesis, anticancer activity, and molecular docking of new pyrazolo [1, 5-a] pyrimidine derivatives

A Hossan, AF Alrefaei, HA Katouah, A Bayazeed… - Journal of Saudi …, 2023 - Elsevier
… The prepared pyrazolo[1,5-a]pyrimidines demonstrated a proper cytotoxicity with significant
growth inhibition of MCF-7 rather than Hep-2. Firstly, pyrazolopyrimidine derivatives 4a-c …

Synthesis of some new pyrazolo[1,5-a]pyrimidine, pyrazolo[5,1-c]triazine, 1,3,4-thiadiazole and pyridine derivatives containing 1,2,3-triazole moiety

NA Abdelriheem, YH Zaki, AO Abdelhamid - Chemistry Central Journal, 2017 - Springer
… The present work depicts an effective synthesis convention of pyrazolo[1,5-a]pyrimidines,
pyrazolo[5,1-c]triazines, thieno[2,3-b]pyridines and polysubstituted pyridines containing …

Synthesis, characterization, antimicrobial activity and anticancer of some new pyrazolo [1, 5-a] pyrimidines and pyrazolo [5, 1-c] 1, 2, 4-triazines

MA Hosny, YH Zaki, WA Mokbel… - Medicinal …, 2020 - ingentaconnect.com
… to the synthesis of different fused pyrazoles for medicines [26-30], Herein, we report the
synthesis of some new thiazoles and pyrazolo[1,5-a]pyrimidines and pyrazolo[5,1-c]triazine. …