[HTML][HTML] Synthetic metabolism for biohalogenation
A Cros, G Alfaro-Espinoza, A De Maria, NT Wirth… - Current opinion in …, 2022 - Elsevier
… deploying synthetic metabolism tailored for biohalogenation … selection of functional metabolic
modules that harness the … bacteria for in vivo biohalogenation. By rationally combining …
modules that harness the … bacteria for in vivo biohalogenation. By rationally combining …
Expanding beyond canonical metabolism: interfacing alternative elements, synthetic biology, and metabolic engineering
… synthetic biology along with metabolic engineering to expand the chemical reach of cellular
metabolism. … with a primary focus on synthetic approaches and promising routes for future …
metabolism. … with a primary focus on synthetic approaches and promising routes for future …
Recent advances in synthetic application and engineering of halogenases
H Minges, N Sewald - ChemCatChem, 2020 - Wiley Online Library
… Biohalogenation occurs on a large variety of organic scaffolds, for … synthesis of halogenated
amino acids has been reported the first time by the group of Wendisch.109 Metabolic …
amino acids has been reported the first time by the group of Wendisch.109 Metabolic …
Halogenases: a biotechnological alternative for the synthesis of halogenated pharmaceuticals
… of halogenating enzymes involved in the synthesis of these halogenated metabolites. In this
… evolution; on the other hand, metabolic pathway engineering has been used to improve the …
… evolution; on the other hand, metabolic pathway engineering has been used to improve the …
Halogenases for biosynthetic pathway engineering: Toward new routes to naturals and non-naturals
BRK Menon, D Richmond, N Menon - Catalysis Reviews, 2022 - Taylor & Francis
… [Citation23] Most reported biohalogenation reactions are with … Here, we provide an
overview of synthetic biology and … control via synthetic promotors, designing metabolic division …
overview of synthetic biology and … control via synthetic promotors, designing metabolic division …
Intersecting xenobiology and neometabolism to bring novel chemistries to life
M Nieto‐Domínguez, PI Nikel - ChemBioChem, 2020 - Wiley Online Library
… Tryptophan is a preferred target molecule of biohalogenation pathways, and halogen … Cl,
Br and I may hinder broad applications in engineering synthetic metabolism (or, for that matter, …
Br and I may hinder broad applications in engineering synthetic metabolism (or, for that matter, …
Cryptic halogenation reactions in natural product biosynthesis
… For the most part, biohalogenation reactions are metabolic endpoints in nature. That is,
however, often not the case in synthetic organic chemistry. The installment of a halogen can be a …
however, often not the case in synthetic organic chemistry. The installment of a halogen can be a …
Enzymatic halogenation: a timely strategy for regioselective C− H activation
C Schnepel, N Sewald - Chemistry–A European Journal, 2017 - Wiley Online Library
… present in metabolic pathways for the sustainable synthesis of … of efficient synthetic pathways
consisting of biohalogenation … this study is not directly connected to biohalogenation, as the …
consisting of biohalogenation … this study is not directly connected to biohalogenation, as the …
Halogenases: powerful tools for biocatalysis (mechanisms applications and scope)
DS Gkotsi, J Dhaliwal, MMW McLachlan… - Current Opinion in …, 2018 - Elsevier
… cost-effective synthesis, and it is imperative that new enzymes are discovered and developed
for process. In contrast to synthetic … This is a breakthrough in the field of biohalogenation. …
for process. In contrast to synthetic … This is a breakthrough in the field of biohalogenation. …
Macroalgal microbiomes unveil a valuable genetic resource for halogen metabolism
… Nonetheless, little is known about the metabolic … putida is a clear example of synthetic
biology [26]. This approach … related to halo- and dehalogenation metabolism, annotated using a …
biology [26]. This approach … related to halo- and dehalogenation metabolism, annotated using a …