… We found Ewing’s sarcoma cell lines, overall, were more sensitive to the PARP inhibitor
olaparib than osteosarcoma cell lines; however, while the effect was in the same direction as the …

… Because cancer therapeutics often target DNA synthesis or repair, we asked if mutational …
make useful markers of drug sensitivity. We detect mutational signatures in cancer cell line …

… from “Systematic identification of genomic markers of drug sensitivity in cancer cells” by …
effect of 130 drugs on 639 cancer-derived cell lines in order to identify novel interactions for …

… from “Systematic identification of genomic markers of drug sensitivity in cancer cells” by …
effect of 130 drugs on 639 cancer-derived cell lines in order to identify novel interactions for …

… to systematically evaluate cell lines as tumor models. We further integrated cell line
proteogenomic data with drug sensitivity … and to connect tumor proteomic subtypes to drug …

… enormous opportunities to systematically identify DRA biomarkers. For … identify gene
expressions, co-expressions, and co-expression modules differentially changed with drug sensitivity…

… The connection between high FAM83H expression and responsiveness to the EGFR
inhibitor erlotinib was validated by gene silencing and from the data set at the Cancer Cell Line …

… that cancer cell … cancer cells and A549 lung cancer cells. In accordance with our LENP
prediction, overexpression of EPIC1 led to the drug resistance of iBET in MCF-7 and A549 cells (…

… cancer cell lines and patient tumors due to their difference in … the prediction of drug sensitivity
using cell lines and patient tumor-… marker-based prediction of drug sensitivity on cancer cell …

… Development of primary drug resistance can make the cancer cells … Using these resistant
cell line models and their isogenic … systematic high throughput drug sensitivity and resistance …