[HTML][HTML] Phagocytic function of tumor-associated macrophages as a key determinant of tumor progression control: a review

M Lecoultre, V Dutoit, PR Walker - Journal for immunotherapy of …, 2020 - ncbi.nlm.nih.gov
phagocytic activity of TAM per se to control tumor progression. Second, we will examine the
potential of TAM to act as antigen presenting cells for tumor specific CD8 T cells, … enhanced. …

Macrophages: their untold story in T cell activation and function

JL Guerriero - International Review of Cell and Molecular Biology, 2019 - Elsevier
… APC, namely macrophages, take up foreign antigen through phagocytosis or through … of
the activation of T cells and consider therapeutically enhancing Signals 1, 2, and 3 that lead to …

Enhancing antibody-dependent cellular phagocytosis by Re-education of tumor-associated macrophages with resiquimod-encapsulated liposomes

H Li, M Somiya, S Kuroda - Biomaterials, 2021 - Elsevier
… is dependent on TAMs. In this study, we found that the M1 type macrophages elicit a more
… by three tumor cell lines, Raji, A431, and SKBR3, along with their corresponding therapeutic …

Higher phagocytic activity of thioglycollate-elicited peritoneal macrophages is related to metabolic status of the cells

S Pavlou, L Wang, H Xu, M Chen - Journal of inflammation, 2017 - Springer
Our results suggest that the elicited macrophages may uptake glucose through Glut-1 to
maintain high metabolic activitiesmacrophages, suggesting that the enhanced phagocytic

Promoting antibody-dependent cellular phagocytosis for effective macrophage-based cancer immunotherapy

X Cao, J Chen, B Li, J Dang, W Zhang, X Zhong… - Science …, 2022 - science.org
macrophages enhanced ADCP of cancer cells, suggesting a role of CSF1R in regulating
macrophage phagocytic … microenvironment, exemplified by T cell immune checkpoint inhibitors …

Antibody-dependent cellular phagocytosis in antiviral immune responses

MZ Tay, K Wiehe, J Pollara - Frontiers in immunology, 2019 - frontiersin.org
… by macrophages leads to enhanced pathogen destruction … collaborators determined that
phagocytosis activity was higher … lack T cells and NK cells, thereby showing lack of dependence

Surface modification of nanoparticles enables selective evasion of phagocytic clearance by distinct macrophage phenotypes

Y Qie, H Yuan, CA Von Roemeling, Y Chen, X Liu… - Scientific reports, 2016 - nature.com
macrophages possess higher phagocytic activities and that … , presentation and subsequently
T lymphocyte priming 2 . … enhanced nanoparticle uptake by activated macrophages. …

PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity

SR Gordon, RL Maute, BW Dulken, G Hutter… - Nature, 2017 - nature.com
phagocytosis by limiting the effector functions of activated TAMs, analogous to the role it
plays in the inhibition of stimulated T cells. … To demonstrate that this enhancement of TAM anti-…

HIV-1 Vpu Promotes Phagocytosis of Infected CD4+ T Cells by Macrophages through Downregulation of CD47

L Cong, SM Sugden, P Leclair, CJ Lim, TNQ Pham… - Mbio, 2021 - Am Soc Microbiol
… on infected CD4 + T cells, leading to enhanced capture and phagocytosis by macrophages.
We … by Vpu promotes enhanced capture and phagocytosis of T cells by monocyte-derived …

Photo-enhancement of macrophage phagocytic activity via Rac1-mediated signaling pathway: Implications for bacterial infection

C Lu, Z Fan, D Xing - The International Journal of Biochemistry & Cell …, 2016 - Elsevier
… In this study, we investigated the effects of LPLI on macrophage phagocytosis. Our results
suggested that LPLI enhances macrophage phagocytic activity by activating the actin …