… TCR cross-reactivity in the induction of autoimmune diseases… Meanwhile, it is clear that also
T cell-mediated immune … This may arise from the relatively low affinity of the induced T cells. …

… -peptides on MHC molecules and assures that T cells expressing TCRs with too low affinity
or too high affinity for “self” (MHC-peptide… to be a T-cell-mediated disease, as autoantibodies …

… (iii) T-cell-mediated tissue destruction along with innate … for MHC/virus peptide to those with
significant cross-reactivity for self. … However, since most T cells will have low affinity for self, …

… T cell cross-reactivity in a human autoimmune disease system hinted toward molecular mimicry
by a more potent pathogenic peptide … low affinity, yet fully functional self-reactive CD8 + T …

… to interleukin (IL)-7 to survive and may bind with low affinity … ACD represents the characteristic
example of a T cell-mediated … T cell epitopes and TCR cross-reactivity for Ni, Co and Pd. …

… peptide cathelicidin upon exposure to commensal bacteria … (CNS) autoimmunity and
cross-reactivity between gut microbial … of various autoimmune diseases with commensal bacteria. …

… that T cells can recognize peptide and non-peptide antigens, … peptide-specific TCRs exhibit
high levels of cross-reactivity. … note that due to challenges involved in measuring low affinity …

… of cross-reactivity between myelin based protein (MBP) self-peptide and two microbial peptides
… While, on other hand, a negative consequence can be for causing autoimmune diseases …

… Based on this cross-reactivity, we hypothesized that P. … distasonis–colonized NOD mice
was T cell mediated, we … link to gut antigens and autoimmune diseases with the potential to …

… very low-affinity interactions between the TCR and peptide–… To visualize how these
TCRs mediate broad cross-reactivity, … An initial T cell-mediated event could precipitate an …