… TNF secretion following TLR4 or TLR7/TLR8 activation and a … cytokine secretion from both
CD4 + and CD8 + T cells in the … a possible defect in the IL-10 pathway in this cell population. …

… , they differentiate into macrophages or dendritic cells (DCs) (4). … -activated protein kinase
and displays defective nuclear … 1 cytokine secretion by measuring IL-27 and TNFα secretion in …

… and can even restore defective type I cytokine secretion in the … a TLR7/TLR8 agonist could
elicit significant IL-12 secretion … 2A and B) but without any increase in HLA-DR+ cells (P > 0.05…

… by increasing their proliferation, cytokine production and … on dendritic cells, macrophages
and neutrophils cells, activated … TLR8 but not TLR7 agonists increased cytokine production …

… perforin-deficient BMDCs with CD8 + T cells and evaluated … by inhibiting the production of
IL-12, TNF-α and IL-6 in BMDCs … Here, we developed Aire-modified dendritic cells to treat type …

… secretion of proinflammatory cytokines by activating immune … may then contribute to
defective virus eradication. These … receptor type 3; DCs, dendritic cells; F4/80, mouse epidermal …

… that neonatal monocytes, dendritic cells, and macrophages … may not be associated with
deficient expression of the targets … capacity of the TLR7/TLR8 agonist CL097 and its antiviral …

… plasmacytoid dendritic cells (pDCs) results in the production … -c, and the production of
IFN-α2 and IL-6 was assessed with … -deficient patients is the impairment of type I IFN production …

… and plasmacytoid dendritic cells (pDCs), deficient IFN-α secretion, and impaired B … of
TNF-α, IL-6, and IL-12 [6]. In our CVID patients, activation via TLR7/TLR8 caused an in vitro …

… in purified human plasmacytoid dendritic cells from blood and … S1H) activated by the
TLR7/TLR8 synthetic stimulator R848 … , TNF-α, and IL-6 protein production, we evaluated the effect …