Tachykinin antagonists ameliorate surgically induced impairment of gastrointestinal motility in rats

A Umer, H Ługowska‐Umer… - Fundamental & …, 2021 - Wiley Online Library
… It has been shown that the potency order of tachykinins is the following: SP> NKA > NKB for
NK … Tachykinins modulate many GI functions including motor activity, mucosal water and ion …

Role of substance P in the cardiovascular system

E Mistrova, P Kruzliak, MC Dvorakova - Neuropeptides, 2016 - Elsevier
… of the tachykinins. Data on the distribution and localization of neuronal … cardiac nervous
system is a complex neural network composed of ganglionated plexuses, which is modulated by …

Tachykinins Play a Major Role in Micro and Macrovascular Complications in Type 2 Diabetes Patients

F Ramzan, L Kiran, SN Malik… - Current Diabetes …, 2024 - ingentaconnect.com
… vessels in the body, it causes destruction in the coronarymodulators released from CGRP
and also called tachykinin [… The key point in the vascular concept is abnormal blood flow of the …

[图书][B] The endothelium: modulator of cardiovascular function

TF Luscher, PM Vanhoutte - 2020 - taylorfrancis.com
… of several autacoids which can affect local blood flow and capillary permeability.Thus, the
… Guinea pig basilar artery Pig coronary artery Dog coronary artery (a2-receptor) Rabbit aorta …

Insect heart rhythmicity is modulated by evolutionarily conserved neuropeptides and neurotransmitters

JF Hillyer - Current opinion in insect science, 2018 - Elsevier
… There is also evidence that tachykinin, pyrokinin, myoinhibitory peptides, … cardiac cells to
modulate heart physiology remains largely unknown. Also, few studies have focused on cardiac

[PDF][PDF] Tachykinin NK2 receptor expression and activity in human colonic smooth muscle: an insight into the influence of gender, sex hormones and diverticular …

S Drimousis - 2019 - unsworks.unsw.edu.au
… secretions and blood flow. Sympathetic … modulation of peristalsis by tachykinin receptor
agents in vivo and in vitro provides further support for the involvement of endogenous tachykinins

Antagonism of the neurokinin-1 receptor improves survival in a mouse model of sepsis by decreasing inflammation and increasing early cardiovascular function

JR Mella, E Chiswick, D Stepien, R Moitra… - Critical care …, 2017 - journals.lww.com
… neuropeptide belonging to the tachykinin family, plays an integral … senses local blood flow
at the level of the carotid artery to … We have demonstrated that modulating the inflammatory …

Intratracheal administration of mesenchymal stem cells modulates tachykinin system, suppresses airway remodeling and reduces airway hyperresponsiveness in an …

K Urbanek, A De Angelis, G Spaziano, E Piegari… - PLoS …, 2016 - journals.plos.org
… neuroinflammatory system can be modulated by cell therapy … approaches, pointing to
tachykinin receptor antagonism as a … role of the interaction of tachykinin receptors, NK1-R and NK2…

Substance P-mediated cardiac mast cell activation: An in vitro study

SP Levick, GL Brower, JS Janicki - Neuropeptides, 2019 - Elsevier
… of the tachykinin family of neuropeptides, including NKA and HK-1; and 2) by examining
the ability of non-tachykinin mediators to modulate the effects of SP activation on cardiac MCs. …

Neprilysin inhibition in heart failure: mechanisms and substrates beyond modulating natriuretic peptides

E D'Elia, A Iacovoni, M Vaduganathan… - European journal of …, 2017 - Wiley Online Library
… of the tachykinincoronary arteries, as well as in coronary artery endothelial cells, may
suggest that this neuropeptide is ideally placed to be released in response to changes in coronary