IFNγ enhances cytotoxic efficiency of the cytotoxic T lymphocytes against human glioma cells
S Shao, E Risch, D Burner, L Lu, B Minev… - International …, 2017 - Elsevier
… imDCs were generated from HLA-A2 positive peripheral blood mononuclear cells (PBMC) …
cytokine targets the human glioma cells to the CTLs we generated with the modified human …
cytokine targets the human glioma cells to the CTLs we generated with the modified human …
Natural killer cells in cancer immunotherapy
JS Miller, LL Lanier - Annual review of cancer biology, 2019 - annualreviews.org
… on NK cells and T cells provide attractive targets for the … natural killer-resistant fresh
solid tumor cells by interleukin 2-activated autologous human peripheral blood lymphocytes …
solid tumor cells by interleukin 2-activated autologous human peripheral blood lymphocytes …
Large-scale isolation and cytotoxicity of extracellular vesicles derived from activated human natural killer cells
AY Jong, CH Wu, J Li, J Sun, M Fabbri… - Journal of …, 2017 - Taylor & Francis
… are activated in target cells after incubation with aNK cell-derived EVs… Peripheral blood
mononuclear cells (PBMC) were isolated by … human cytotoxic T lymphocytes and NK cells secrete …
mononuclear cells (PBMC) were isolated by … human cytotoxic T lymphocytes and NK cells secrete …
Human lung natural killer cells are predominantly comprised of highly differentiated hypofunctional CD69− CD56dim cells
… resident lymphocytes, including T cells and NK cells,… target cells compared with NK cells in
peripheral blood (Fig 2, C), indicating that the former were impaired both in natural cytotoxicity …
peripheral blood (Fig 2, C), indicating that the former were impaired both in natural cytotoxicity …
In vitro safety assessment of the strawberry tree (Arbutus unedo L.) water leaf extract and arbutin in human peripheral blood lymphocytes
… Studies focused on in vitro genotoxicity of other polyphenol constituents present in A. unedo
… To establish the levels of DNA damage in treated lymphocytes, we focused on two comet …
… To establish the levels of DNA damage in treated lymphocytes, we focused on two comet …
Natural killer cells and other innate lymphoid cells in cancer
L Chiossone, PY Dumas, M Vienne… - Nature Reviews …, 2018 - nature.com
… studies have shown peripheral blood natural cytotoxicity to be … that aimed to restore
intratumoural NK cell-mediated cytotoxicity … It should be noted that the lack of tumour lymphocyte …
intratumoural NK cell-mediated cytotoxicity … It should be noted that the lack of tumour lymphocyte …
Investigation of genetic toxicity and oxidative stress of Clostridium perfringens epsilon toxin type D on human peripheral blood lymphocytes
M Shokrzadeh, A Zeyar, R Golmohammadi… - Microbial …, 2021 - Elsevier
… target tissues and cells of the host organism, pathogenic bacteria behave differently. Between
them, toxin production creates an efficient way to modify specific functions of target cells. …
them, toxin production creates an efficient way to modify specific functions of target cells. …
[HTML][HTML] The role of natural killer cells in hepatocellular carcinoma development and treatment: A narrative review
S Juengpanich, L Shi, Y Iranmanesh, J Chen… - Translational …, 2019 - Elsevier
… studies have shown that targeting Natural Killer cells, as major … Peripheral blood Natural
Killer cells can be expanded and … of cytotoxicity of Natural killer cells and CD8 + T lymphocytes …
Killer cells can be expanded and … of cytotoxicity of Natural killer cells and CD8 + T lymphocytes …
iPSC-derived natural killer cell therapies-expansion and targeting
… sources each possess advantages and disadvantages for use in cellular therapy targeting
cancer (30). Peripheral blood NK (PB-NK) cells must be collected from a donor by apheresis …
cancer (30). Peripheral blood NK (PB-NK) cells must be collected from a donor by apheresis …
Natural killer cell immunotherapies against cancer: checkpoint inhibitors and more
… drug targeting in vivo include natural killer (NK) cells. These … of total peripheral blood
mononuclear cells (PBMCs) in humans … ) are also expressed by cytotoxic T lymphocytes, and mAb …
mononuclear cells (PBMCs) in humans … ) are also expressed by cytotoxic T lymphocytes, and mAb …