[HTML][HTML] The role of natural killer cells in hepatocellular carcinoma development and treatment: A narrative review

S Juengpanich, L Shi, Y Iranmanesh, J Chen… - Translational …, 2019 - Elsevier
… studies have shown that targeting Natural Killer cells, as major … Peripheral blood Natural
Killer cells can be expanded and … of cytotoxicity of Natural killer cells and CD8 + T lymphocytes

In vitro safety assessment of the strawberry tree (Arbutus unedo L.) water leaf extract and arbutin in human peripheral blood lymphocytes

K Jurica, I Brčić Karačonji, A Mikolić… - Cytotechnology, 2018 - Springer
… Studies focused on in vitro genotoxicity of other polyphenol constituents present in A. unedo
… To establish the levels of DNA damage in treated lymphocytes, we focused on two comet …

Human lung natural killer cells are predominantly comprised of highly differentiated hypofunctional CD69− CD56dim cells

N Marquardt, E Kekäläinen, P Chen… - Journal of allergy and …, 2017 - Elsevier
… resident lymphocytes, including T cells and NK cells,… target cells compared with NK cells in
peripheral blood (Fig 2, C), indicating that the former were impaired both in natural cytotoxicity

Natural killer cells and other innate lymphoid cells in cancer

L Chiossone, PY Dumas, M Vienne… - Nature Reviews …, 2018 - nature.com
… studies have shown peripheral blood natural cytotoxicity to be … that aimed to restore
intratumoural NK cell-mediated cytotoxicity … It should be noted that the lack of tumour lymphocyte

Targeting natural killer cells in cancer immunotherapy

C Guillerey, ND Huntington, MJ Smyth - Nature immunology, 2016 - nature.com
… They represent 5–15% of circulating lymphocytes in humanscells with high cytotoxic potential
are predominant in human … of NK cells from peripheral blood, the sensitivity of NK cells to …

Natural killer cells in inflammation and autoimmunity

B Zitti, YT Bryceson - Cytokine & Growth Factor Reviews, 2018 - Elsevier
… Their activation does not only involve target cell killing through release of perforin- and …
constitute 5–15% of all lymphocytes. Approximately 10% of peripheral blood NK cells express …

Natural killer cells target and differentiate cancer stem-like cells/undifferentiated tumors: strategies to optimize their growth and expansion for effective cancer …

K Kaur, MP Nanut, MW Ko, T Safaie, J Kos… - Current opinion in …, 2018 - Elsevier
Natural killer (NK) cells are large granular lymphocytes with the ability to lyse tumors and/or …
NK cells obtained from peripheral blood of humans express CD16 +++ CD56 + CD69 − …

iPSC-derived natural killer cell therapies-expansion and targeting

BH Goldenson, P Hor, DS Kaufman - Frontiers in immunology, 2022 - frontiersin.org
… sources each possess advantages and disadvantages for use in cellular therapy targeting
cancer (30). Peripheral blood NK (PB-NK) cells must be collected from a donor by apheresis …

Targeting the tumor microenvironment to improve natural killer cell-based immunotherapies: On being in the right place at the right time, with resilience

S Murray, A Lundqvist - Human Vaccines & Immunotherapeutics, 2016 - Taylor & Francis
… of a cellular target. Later work established that NK cells are innate lymphocytes with some …
preferentially accumulate in tumor tissue rather than in peripheral blood in patients with RCC, …

Melittin induced cytogenetic damage, oxidative stress and changes in gene expression in human peripheral blood lymphocytes

G Gajski, AM Domijan, B Žegura, A Štern, M Gerić… - Toxicon, 2016 - Elsevier
… Nevertheless, there is not much information on its effects on normal cells and the … study
aimed to investigate the cyto/genotoxic activity of MEL in human peripheral blood lymphocytes (…