… -cell epigenetic variation in early mouse and human … -target methylation at on-target promoters
as the direct fusion-based editing tool (dCas9-D3A), but much lower off-target methylation …

… target promoter regions during embryonic development and … DNA methylation dynamics
during early mouse development … (red) and paternal (blue) methylation. This indicates the major …

… promoter and promote transcription. The DNA methylation from the ICR spreads into the H19
promoter, … A later, second wave targets these initially resistant regions, leading to the lowest …

… at CpG-rich promoters, gene bodies and transposable elements. We highlight the dynamic
erasure and re-establishment of DNA methylation … , the main targets of DNA methylation in …

… the dynamics of DNA methylation in human and mouse. The … in gametes and early mouse
embryos and by methylation analyses in … more directly should be an exciting goal for the future. …

… of DNA methylation profiles at promoters and enhancers, we find that DNMT3A2 and DNMT3B1
are preferentially bound to silent promoters … and DNA methylation is that EZH2 targets …

… by DNA methylation of their target sequences. … promoter methylation arrays, Calvanese
and coworkers identified hematopoietic-specific genes repressed by promoter DNA methylation …

… DNA methylation landscape in the developing mouse … We linked CG-DMRs to their putative
target genes on the basis … First, we overlapped CG-DMRs with promoters, CGIs and CGI …

… of these elements, we determined their target genes. Distal UMRs, such as those at non-promoter
CGIs, and LMRs were putatively assigned to target genes. We used the 4DGenome …

… in promoter regions, are usually devoid of methylation [2]. … the highly dynamic and regulated
processes of DNA demethylation … only loss of methylation, mostly at DNMT3A target loci, in a …