… affecting the telomerase-mediated telomere maintenance pathway, … and requires CST–Polα/Primase-mediated
fill-in. (… In vitro, CST–Polα/Primase does initiate with a major RNA product, …

… solely from the coupling of telomerase-mediated G strand synthesis and C … DNA replication
reactions in vitro containing purified DNA polymerase α/primase and artificial template DNA…

… as substrates for telomerase-mediated telomere elongation. … to promote C-strand fill-in,
POT1b is also required to promote … (mTERT) in vitro and localizes to mouse telomeres in the …

… This replication requires telomerase 3 extension of the single-stranded DNA (ssDNA) of the
… in vivo, where the products made by Polα–primase are transferred to DNA polymerase 𝛿 for …

… Using in vitro conditions close to physiological states, it has … stimulation of the DNA Pol
α–primase complex facilitates the fork … complications due to telomerase-mediated over elongation …

… POT1-TPP1 complex, which regulates telomerase-mediated G-strand synthesis. … telomere
evolution that gives prominent considerations to the roles of CST, primase-Pol α, and telomere …

… Because telomerase requires a 3′ overhang in vitro (26), we anticipated that neotelomere
formation would require the MRN (Mre11/Rad50/Nbs1)/CtIP–mediated endonucleolytic …

… Pol α-primase binding appears to be required for nuclear … of the telomeric G-strand to pol
α-primase synthesis of the C-… from elongating DNA under multiple in vitro conditions, the switch …

… Neither group directly assessed the capacity of Cdc13 to bind the seed sequence in vitro,
so … is required for non-homologous end joining, promotes dnTA through interaction with the …

… C-strand by DNA polymerase α-primase (pol α) 12 . This … In vitro studies indicate CST
enhances pol α priming by … is to prevent excess telomerase-mediated repeat addition. Since the …