… of CYR61 in early angiogenesis as well as chondrogenesis. … -fracture day, we could observe
the decline of expression by … CYR61 showed different temporal mRNA as well as protein …

… on cartilage matrix deposition in a transforming growth factor (TGF)-β1-induced pellet
chondrogenesis assay and osteogenic gene induction in an osteogenic medium differentiation …

… Conclusion: We conclude that CYR61 expression provides an early prediction of … Temporal
expression of the chondrogenic and angiogenic growth factor CYR61 during fracture repair. J …

… This is followed by the expression of growth factors bone … neo-angiogenesis, chondrogenesis
and callus formation during the … , while growth factor markers including BMP-2 and CYR61 …

… chondrogenic differentiation does not require Plg contribution. … and activate Cyr61, a
matrix‐associated growth factor that is … We speculate that Plg/Cyr61‐mediated angiogenesis may …

… pathways and transcription factors expressed at each time … In this study, CTGF and CYR61
(Cluster 45) were significantly … stages of fracture repair (inflammation and chondrogenesis) [44…

… We generated acute soft tissue trauma with temporary ischemia … is not mitogenic by itself, it
may synergize with growth factors … suggesting that CYR61 improves angiogenesis after acute …

… both temporally and spatially differentially expressed during … system (ie, during fracture
repair, osteogenic and chondrogenic … transcription factor, was found to be normally expressed in …

… three transcription factors: Runt-related transcription factor 2 (… endochondral ossification from
early chondrogenesis at D5 to … Angiogenesis is an important component of fracture healing …

… growth factor and a slightly lowered expression of bone … CYR61 expression corresponds
with active chondrogenesis. … fracture model that CYR61 expression during fracture repair …