Glial interleukin-1β upregulates neuronal sodium channel 1.7 in trigeminal ganglion contributing to temporomandibular joint inflammatory hypernociception in rats

P Zhang, RY Bi, YH Gan - Journal of neuroinflammation, 2018 - Springer
… TMJ inflammation activates glial cells in both the TG and … Here, we showed that TMJ
inflammation activated trigeminalcells that can produce TNF-α, and infiltrating immune cells, …

[PDF][PDF] … factor alpha signaling in trigeminal ganglion contributes to mechanical hypersensitivity in masseter muscle during temporomandibular joint inflammation

R Ito, M Shinoda, K Honda, K Urata, J Lee… - J Oral Facial Pain …, 2018 - files.jofph.com
both the increased number of TG cells encircled by activated … Various immune cells appear
in the TMJ region during TMJ … Satellite glial cells (SGCs) are also activated in the trigeminal

TNFα in the trigeminal nociceptive system is critical for temporomandibular joint pain

Q Bai, S Liu, H Shu, Y Tang, S George, T Dong… - Molecular …, 2019 - Springer
… is an inflammatory mediator produced by activated immune cells, … glia-neuron crosstalk
during the CFA-induced TMJ pain because it was exclusively expressed on the neurons in both

Propargylglycine decreases neuro-immune interaction inducing pain response in temporomandibular joint inflammation model

…, DP Ferrari, CP Capel, HDC Francescato, TM Coimbra… - Nitric oxide, 2019 - Elsevier
… increased activation of glial cells in the trigeminal ganglia on the 14th day of inflammation can
… production in both, TMJ and TG tissue, contributing to TMJ inflammatory hypernociception. …

[HTML][HTML] … ROLE OF PROTEIN KINASE A IN PROMOTING TRIGEMINAL NOCICEPTION IN AN IN VIVO MODEL OF TEMPOROMANDIBULAR JOINT DISORDER

LK Koop, JL Hawkins, LE Cornelison… - … of oral & facial pain …, 2017 - ncbi.nlm.nih.gov
… and activation of nociceptive neurons and glial cells via … the STN in promoting cellular
changes in trigeminal neurons … The inflammatory mediator CFA was injected into both joint

[HTML][HTML] Temporomandibular joint arthritis increases canonical Wnt pathway expression in the articular cartilage and trigeminal ganglion in rats

LM de Sousa, AC de Figueiredo Costa, AF Pereira… - Bone Reports, 2023 - Elsevier
… This study showed that both Wnt10b and β-catenin … activation of the nociceptive pathway.
An increased c-Fos expression was observed in the trigeminal ganglion, that contains the cell

Neuroimmune and Systemic Manifestations of Neuroinflammation in the Temporomandibular Joint and Related Disorders

A Barkhordarian, F Chiappelli… - Temporomandibular Joint …, 2018 - Springer
… The immune system functions under two principal branches … in activation of second-order
neurons and glial cells that cause … of immune cells, and activation of trigeminal nociceptors …

Tumor necrosis factor-Alpha stimulates cytokine expression and transient sensitization of trigeminal nociceptive neurons

ZL Durham, JL Hawkins, PL Durham - Archives of oral biology, 2017 - Elsevier
… -α) in the capsule of the temporomandibular joint (TMJ) are … within the TMJ by both immune
and non-immune cells such as … dependent on the activation of the satellite glial cells, which …

Expression of CGRP in the Trigeminal Ganglion and Its Effect on the Polarization of Macrophages in Rats with Temporomandibular Arthritis

J Tao, X Wang, J Xu - Cellular and Molecular Neurobiology, 2024 - Springer
… and neuronal cell bodies serves to activate other neurons and satellite glial cells through …
These immune cells promote tissue homeostasis by transitioning their phenotype from the …

Sustained and repeated mouth opening leads to development of painful temporomandibular disorders involving macrophage/microglia activation in mice

GYF Wang, XQ Shi, W Wu, M Gueorguieva, M Yang… - Pain, 2018 - journals.lww.com
… conditions involving the temporomandibular joint (TMJ) and/or … inflammation and CNS glia
cells in maintaining chronic paintrigeminal ganglia and microglia activation in the trigeminal