Upregulation and activation of δ‑opioid receptors promotes the progression of human breast cancer

YC Wei, B Zhang, X Li, XM Liu, J Zhang… - Oncology …, 2016 - spandidos-publications.com
µ-opioid receptor gene polymorphism observed in breast cancer is a highly significant risk
factor for the development … is related to the effect of DOR on breast cancer progression, we …

Opioids in cancer: The κ‑opioid receptor

Q Zhou, Z Zhang, S Long, W Li… - Molecular …, 2022 - spandidos-publications.com
… types of cancer and may influence cancer progression. … of µ-opioid receptor (MOR) in lung
cancer samples with metastasis was found to be significantly higher than that in lung cancer

Opioid receptor-mediated and non-opioid receptor-mediated roles of opioids in tumour growth and metastasis

CA Scroope, Z Singleton, MW Hollmann… - … in Oncology, 2021 - frontiersin.org
… -µ opioid receptor mediated (54). Another study indicated MNTX potentiated the effect of the
anti-tumour drug docetaxel in gastric cancerreceptor function to cancer risk or prognosis in …

The µopioid receptor in cancer and its role in perineural invasion: a short review and new evidence

JP Cata, ML Uhelski, A Gorur, S Bhoir, N Ilsin… - Advanced …, 2022 - Wiley Online Library
cancer progression by acting on cancer cells or the tumor microenvironment. The μ-opioid
receptor is the site of action … the role of the μ-opioid receptor in cancer growth is summarized …

The Role of Opioid Receptors in Cancer

S Bhoir, M Uhelski, JJ Guerra‐Londono… - Advanced …, 2023 - Wiley Online Library
µ-opioid receptor-mediated cancer progression, discuss the underlying cellular and molecular
mechanisms of the biology of cancer progressionµ-opioid receptor for anticancer therapy. …

Targeting the mu-opioid receptor for cancer treatment

H Zhang, D Zhou, J Gu, M Qu, K Guo, W Chen… - Current Oncology …, 2021 - Springer
… Next, we will introduce its role in the progression of tumor. … Opioids have direct effects on
peripheral immune cells. Bryant et al. [… The μ-opioid receptor (MOR) promotes tumor initiation in …

Opioid receptors beyond pain control: The role in cancer pathology and the debated importance of their pharmacological modulation

M Carli, S Donnini, C Pellegrini, E Coppi… - Pharmacological …, 2020 - Elsevier
… role of opioid receptors in modulating cancer progression, a … They act as μ-opioid receptor
(MOP) agonists, but also show … Together with these direct effects of opioids on immune cells, …

The effect of anesthetic technique on µ-opioid receptor expression and immune cell infiltration in breast cancer

KJ Levins, S Prendeville, S Conlon, DJ Buggy - Journal of anesthesia, 2018 - Springer
… cells and μ-opioid receptors (MOR) within cancer tissue can predict cancer prognosis. No …
by the paravertebral block or indeed by the direct effect of the local anesthetic on sodium …

Perioperative immunosuppression and risk of cancer progression: the impact of opioids on pain management

R Zajączkowska, W Leppert, J Mika… - Pain Research and …, 2018 - Wiley Online Library
… This may result in an increased risk of cancer progression. However, the test … direct effect
of opioids on cancer cells observed in experimental studies translates into comparable effects

The role of opioids in cancer progression

MF Ramirez, A Gorur, JP Cata - International anesthesiology …, 2020 - journals.lww.com
… period is a window of opportunity for cancer progression and metastasis. The answer is …
the direct effects of analgesics and anesthetics can interact to promote cancer progression. …