… The overall study design and protocol of the CRASH-2 trial have been previously reported.3,
6 In summary, 20,111 adults with or at risk of significant traumatic bleeding within 8 hours of …

… Randomised trial and economic evaluation. Patients were assigned by … analysis of
administering tranexamic acid to bleeding trauma patients using evidence from the CRASH-2 trial. …

… Large randomised controlled trials (RCTs) have shown its … in the trial protocol, we present
an economic evaluation of … be 21 min (as per the CRASH-2 trial, involving the same treatment …

… was ongoing during the time window of our TARN data analysis, there was clear evidence
from the CRASH-2 trial about the benefits of TXA in trauma patients, and so this would not …

… Because tranexamic acid reduces mortality in extra-cranial bleeding (CRASH-2), the mortality
reduction seen in this trial could be from the extra-cranial injury rather than any effect on …

… randomised controlled trials (RCTs) such as the WOMAN and CRASH-2 and CRASH-3 trials
… after injury in both WOMAN and CRASH-2 and CRASH-3 trials.16 18 Unlike postpartum …

… analysis will explore the use of the EQ-5D data to quality-adjusted survival. In this study, the
economic analysis … study due to available evidence from CRASH 2 study on the same drug. …

… from controlled studies of the possible synergistic effect … : prespecified analysis of data from
randomised controlled trial. … Finally, we should remember that the CRASH-2 study showed …

… findings of the CRASH-2 trial but suggest that incidence rates in adults with trauma in
settings outside of the CRASH-2 trial may be different than those observed in the CRASH-2 trial. …

… CRASH-2 trial collaborators … To identify further published, ongoing, and unpublished
randomised controlled trials we scanned bibliographies of relevant articles and searched …