Proteomic analyses reveal new features of the box H/ACA RNP biogenesis
F Schlotter, S Mérouani, J Flayac, V Kogey… - Nucleic Acids …, 2023 - academic.oup.com
… We performed the analysis of GAR1, NHP2, SHQ1 and NAF1 … -specific H/ACA RNPs (scaRNPs)
structurally resemble H/ACA … Another family of H/ACA RNAs of unknown function is …
structurally resemble H/ACA … Another family of H/ACA RNAs of unknown function is …
Assembly and trafficking of box C/D and H/ACA snoRNPs
S Massenet, E Bertrand, C Verheggen - RNA biology, 2017 - Taylor & Francis
… , while telomerase RNA, which contains H/ACA motifs, functions in … of box H/ACA RNP
assembly is the interaction of SHQ1 with … assembly factor NAF1 that interacts with the CTD of RNA …
assembly is the interaction of SHQ1 with … assembly factor NAF1 that interacts with the CTD of RNA …
[HTML][HTML] In silico characterization and identification of compound heterozygous variants in H/ACA Ribonucleoprotein Assembly Factor (SHQ1) from Indian population
VK Gowda, VM Srinivasan, S Srivastava… - Journal of Family …, 2024 - journals.lww.com
… of SHQ1 with H/ACA RNPs and implicate its crucial role in the … of SHQ1 with NAF1 and
therefore establish the SHQ1 role … and the core trimer associate with H/ACA RNA at the site of …
therefore establish the SHQ1 role … and the core trimer associate with H/ACA RNA at the site of …
SHQ1 regulation of RNA splicing is required for T-lymphoblastic leukemia cell survival
H Su, J Hu, L Huang, Y Yang, M Thenoz… - Nature …, 2018 - nature.com
… role(s) and regulatory mechanism(s). We here show that SHQ1, an H/ACA snoRNP assembly
factor … SHQ1 is also responsible for telomerase RNP assembly and important for telomere …
factor … SHQ1 is also responsible for telomerase RNP assembly and important for telomere …
Dyskerin: an essential pseudouridine synthase with multifaceted roles in ribosome biogenesis, splicing, and telomere maintenance
A Garus, C Autexier - Rna, 2021 - rnajournal.cshlp.org
… of Cbf5, simulating the contacts that Cbf5 has with RNA, thus … Following the discovery of
SHQ1's role in stabilizing newly … with RNAs, the role of two other assembly factors in H/ACA RNP …
SHQ1's role in stabilizing newly … with RNAs, the role of two other assembly factors in H/ACA RNP …
[图书][B] Characterizing the Telomerase-associated and H/ACA Ribonucleoprotein Dyskerin: Regulation and Function
D MacNeil - 2020 - search.proquest.com
… of the H/ACA RNP and its assembly factors, individually … RNA-mimic and chaperone
SHQ1 plays a very early role in human H/ACA RNP biogenesis, upstream of NAF1 and pre-H/ACA …
SHQ1 plays a very early role in human H/ACA RNP biogenesis, upstream of NAF1 and pre-H/ACA …
Human SHQ1 variants R335C and A426V lead to severe ribosome biogenesis defects when expressed in yeast
I Alidou-D'Anjou, A Patel, S Sleiman, F Dragon - Frontiers in Genetics, 2023 - frontiersin.org
… is removed from dyskerin with the assistance of AAA + ATPases to allow RNP assembly at
… also impact the stability of H/ACA snoRNAs. To this end, small RNAs were extracted from the …
… also impact the stability of H/ACA snoRNAs. To this end, small RNAs were extracted from the …
Compound heterozygous variants in SHQ1 are associated with a spectrum of neurological features, including early-onset dystonia
S Sleiman, AE Marshall, X Dong… - Human Molecular …, 2022 - academic.oup.com
… of RNPs that use an RNA guide to pseudouridylate rRNAs; … , some H/ACA RNAs also have
additional functions including … Given SHQ1 is important for assembly of H/ACA snoRNPs, …
additional functions including … Given SHQ1 is important for assembly of H/ACA snoRNPs, …
SHQ1-associated neurodevelopmental disorder: Report of the first homozygous variant in unrelated patients and review of the literature
A AlHargan, MA AlMuhaizea, R Almass… - Human Genome …, 2023 - nature.com
… assembly factor for H/ACA ribonucleoproteins (RNPs) 2 . Therefore, it is involved in various
important functions, … nonspecific RNA binding and aggregation before assembly of H/ACA …
important functions, … nonspecific RNA binding and aggregation before assembly of H/ACA …
The role of Hsp90-R2TP in macromolecular complex assembly and stabilization
J Lynham, WA Houry - Biomolecules, 2022 - mdpi.com
… one copy of … SHQ1 functions as a NAP57 chaperone by acting as an RNA placeholder,
thereby protecting NAP57 from nonspecific RNA binding before its association with H/ACA RNA …
thereby protecting NAP57 from nonspecific RNA binding before its association with H/ACA RNA …