This report gives details of the prevalence of chronic kidney disease (CKD) and liver disease in the adult population, across different social and demographic groups, using self-report and biological measurements. From blood samples, serum creatinine and cystatin C are used to estimate the glomerular filtration rate (eGFR), and from urine, albumin and creatinine are used to calculate an albumin: creatinine ratio, key markers of renal damage. For the first time in HSE, levels of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) in blood samples have been measured. Raised levels of AST or ALT are markers of potential liver damage.