[HTML][HTML] SPON2 is upregulated through notch signaling pathway and promotes tumor progression in gastric cancer

HG Kang, WJ Kim, MG Noh, KH Chun, SJ Kim - Cancers, 2020 - mdpi.com
gastric cancer are still obscure. In this study, we investigated the role of SPON2 and related
signaling pathway in gastric cancer progressionActivated Notch1 enhances gastric cancer

miR‐124 interacts with the Notch1 signalling pathway and has therapeutic potential against gastric cancer

L Jiang, T Lin, C Xu, S Hu, Y Pan… - Journal of cellular and …, 2016 - Wiley Online Library
signalling plays an important role in cancer progression. … and the Notch signalling pathway
and its role in gastric cancer (GC… miR-124 negatively regulated Notch1 signalling by targeting …

Notch1 and PI3K/Akt signaling blockers DAPT and LY294002 coordinately inhibit metastasis of gastric cancer through mutual enhancement

X Peng, J Zhou, B Li, T Zhang, Y Zuo, X Gu - Cancer Chemotherapy and …, 2020 - Springer
… of the Notch1 and PI3K/Akt signal pathways in gastric cancer … DAPT and LY294002 on
metastasis of gastric cancer. DAPT (N-… and inhibits activation of the Notch1 signaling. LY294002 is …

[HTML][HTML] Correlation between HGF/c-Met and Notch1 signaling pathways in human gastric cancer cells

KH Huang, I Sung, WL Fang, CW Chi… - Oncology …, 2018 - spandidos-publications.com
gastric cancer SC-M1 cells (12). However, the role of the interaction between the HGF/c-Met
and Notch1 signaling pathway in gastric cancersignal transduction in SC-M1 gastric cancer

[HTML][HTML] COX-2 regulates Snail expression in gastric cancer via the Notch1 signaling pathway

Y Ye, M Liu, H Yuan, S Ning… - International …, 2017 - spandidos-publications.com
During the initiation and development of various tumours, the Notch family plays a key …
gastric cancer (GC) remains unclear. The present study aimed to clarify the mechanisms through

[HTML][HTML] Luteolin suppresses gastric cancer progression by reversing epithelial-mesenchymal transition via suppression of the Notch signaling pathway

M Zang, L Hu, Z Fan, H Wang, Z Zhu, S Cao… - Journal of translational …, 2017 - Springer
… Real-time reverse transcription polymerase chain reaction (RT-PCR) and Western blots were
performed to evaluate Notch1 signaling and activation of epithelial-mesenchymal transition …

[HTML][HTML] Notch1 pathway-mediated microRNA-151-5p promotes gastric cancer progression

KW Hsu, WL Fang, KH Huang, TT Huang, HC Lee… - Oncotarget, 2016 - ncbi.nlm.nih.gov
… This study showed that Notch1 pathway enhanced gastric carcinogenesis through miR-151-5p
and FAK and Notch1/miR-151-5p/p53 axis contributed to gastric cancer progression (…

[HTML][HTML] Notch and mTOR signaling pathways promote human gastric cancer cell proliferation

ES Hibdon, N Razumilava, TM Keeley, G Wong… - Neoplasia, 2019 - Elsevier
… expression of the NOTCH1 receptor signaling fragment NICD, … mTORC1 signaling reduced
growth of human gastric cancer … with this signaling pathway to promote gastric epithelial cell …

[HTML][HTML] The function of Notch1 intracellular domain in the differentiation of gastric cancer

S Hu, Q Chen, T Lin, W Hong, W Wu… - Oncology …, 2018 - spandidos-publications.com
… Due to the complex function of the Notch signal pathway in gastric cancer (GC), the association
between Notch homolog 1 (Notch1) intracellular domain (NICD) and differentiation of GC …

… overexpression increases gastric cancer stem/progenitor cell self‐renewal ability and correlates with poor clinical outcome via Notch1 signaling pathway activation

ZF Miao, H Xu, HM Xu, ZN Wang, TT Zhao… - Cancer …, 2017 - Wiley Online Library
associated with CSPCs in gastric cancer, and its expression impacts CSPC stemness
characteristics associated with the Notch-1 pathway … , chemoresistance, and tumor formation. Our …