Clinical significance of NOTCH1 intracellular cytoplasmic domain translocation into the nucleus in gastric cancer

S Saito, H Ishiguro, M Kimura… - Biomedical …, 2016 - spandidos-publications.com
activation of the Notch signaling pathway in … signaling pathway is activated in gastric cancer.
In the present study, the aim was to investigate the role of Notch signaling in gastric cancer

ELK4-mediated lncRNA SNHG22 promotes gastric cancer progression through interacting with EZH2 and regulating miR-200c-3p/Notch1 axis

X Mao, T Ji, A Liu, Y Weng - Cell death & disease, 2021 - nature.com
… in gastric cancer The expression levels of SNHG22 were analyzed using TCGA dataset by
… that SNHG22 was upregulated in gastric cancers compared with non-tumor tissues (Fig. 1A). …

Notch signaling pathway networks in cancer metastasis: a new target for cancer therapy

L Li, P Tang, S Li, X Qin, H Yang, C Wu, Y Liu - Medical oncology, 2017 - Springer
Notch-1 signaling pathway was found to be aberrantly … As an oncogene, Notch is
overexpressed in breast cancer [23], gastric cancer [26], pancreatic cancer [24] and colon …

[HTML][HTML] Identification of 8-gene risk prediction signature associated with NOTCH1 in stomach adenocarcinoma based on bioinformatics analysis

D Pan, C Lin, X Lin, L Li - Journal of Gastrointestinal Oncology, 2022 - ncbi.nlm.nih.gov
… type of gastric cancer (GC) with high mortality and poor prognosis. We sought to investigate
the contribution of Notch receptor 1 (NOTCH1) … signaling pathway are associated with gastric

Luteolin suppresses angiogenesis and vasculogenic mimicry formation through inhibiting Notch1-VEGF signaling in gastric cancer

M Zang, L Hu, B Zhang, Z Zhu, J Li, Z Zhu… - Biochemical and …, 2017 - Elsevier
… of gastric cancer cells through suppressing Notch1 signaling. … Notch1 increased VEGF
secretion in Hs-746T gastric cancer … Therefore, we examined whether Notch1 signaling pathway

Palbociclib induces cell senescence and apoptosis of gastric cancer cells by inhibiting the Notch pathway

H Bi, J Shang, X Zou, J Xu, Y Han - Oncology Letters, 2021 - spandidos-publications.com
… The Notch signaling pathway is evolutionarily conserved and can direct cell fate … kinase
activity plays a key role in the onset of T cell acute lymphoblastic leukemia via Notch1 activation

… of midkine gene promotes the antitumoral effect of cisplatin on human gastric cancer cell line AGS in vitro and in vivo via the modulation of Notch signaling pathway

W Tian, J Shen, W Chen - Oncology Reports, 2017 - spandidos-publications.com
… MK was expressed in gastric carcinoma tissues and cancer cells. The cytotoxic effect of … MK
expression via downregulating the Notch signaling pathway-related proteins (Notch 1, Notch …

Prognostic value of NOTCH1 and OCT4 in gastric carcinoma

DA Ibrahim, EA Elsebai, A Fayed… - Indian Journal of …, 2022 - journals.lww.com
… revealed that NOTCH1 upregulation was associated with … revealed that activation of
NOTCH signaling pathway may … that NOTCH1 signaling pathway and OCT4 were activated in …

Gamma-Secretase Inhibitor IX (GSI) Impairs Concomitant Activation of Notch and Wnt-Beta-Catenin Pathways in CD44+ Gastric Cancer Stem Cells

S Barat, X Chen, K Cuong Bui, P Bozko… - Stem cells …, 2017 - academic.oup.com
… catenin pathways are a group of signal transduction pathways … wnt signaling pathways are
the canonical wnt pathway or b-… via Notch1 mediated inhibiton of the concomitant activation of …

[HTML][HTML] Crosstalk between the Notch signaling pathway and non‑coding RNAs in gastrointestinal cancers

Y Pan, Y Mao, R Jin, L Jiang - Oncology Letters, 2018 - spandidos-publications.com
… loop between miR-124 and the Notch1 signaling pathway in gastric cancer cells (40). miR-…
downregulated in gastric cancer tissues compared with adjacent normal gastric tissues, and …