[HTML][HTML] MECP2 promotes the migration and invasion of gastric cancer cells by modulating the Notch1/c-Myc/mTOR signaling pathways by suppressing FBXW7 …

L Zhao, X Wang, J Yang, Q Jiang, J Zhang… - … Journal of Cancer …, 2022 - ncbi.nlm.nih.gov
… The present study revealed that by regulating the FBXW7/Notch1 signaling pathway, …
cells by regulating the Notch1/c-Myc/mTOR signaling pathways through inhibition of FBXW7 …

NOTCH3, a crucial target of miR-491-5p/miR-875-5p, promotes gastric carcinogenesis by upregulating PHLDB2 expression and activating Akt pathway

W Kang, J Zhang, T Huang, Y Zhou, CC Wong… - Oncogene, 2021 - nature.com
… comprehensively reveal its deregulation in gastric cancer (GC). In … Furthermore, Notch
signaling pathway is activated after H. … of NOTCH1-4 in primary gastric tumors and normal gastric

… demethylase GASC1 inhibitor targeted GASC1 gene to inhibit the malignant transformation of esophageal cancer through the NOTCH-MAPK signaling pathway

Q Li, B Qu, H Shen, H Deng… - Annals of Clinical & …, 2022 - Assoc Clin Scientists
… Esophageal cancer is a common gastrointestinal tumor, with high incidence in our country.
Histone … Notch1 is the main receptor of Notch signaling pathway and is closely related to cell …

Changes in NOTCH1 gene and its regulatory circRNA, hsa_circ_0005986 expression pattern in human gastric adenocarcinoma and human normal fibroblast cell line …

F Mansoury, N Babaei, S Abdi, M Entezari… - … Biology and Medicine, 2021 - Taylor & Francis
NOTCH1 and its regulatory circ-RNA, hsa_circ_0005986, in human gastric adenocarcinoma
… the Notch signaling pathway reduces gastric epithelial cells by impacting on the mTORC1 …

MicroRNAs are involved in the development and progression of gastric cancer

X Liu, R Ma, B Yi, AI Riker, Y Xi - Acta Pharmacologica Sinica, 2021 - nature.com
… studies related to the regulatory mechanisms of gastric tumorinto the mechanistic role of
miRNAs in GC development and … PI3K/Akt/mTOR) signaling pathway is important for regulating …

miR-935 suppresses gastric signet ring cell carcinoma tumorigenesis by targeting Notch1 expression

C Yan, J Yu, W Kang, Y Liu, Z Ma, L Zhou - Biochemical and biophysical …, 2016 - Elsevier
… -935 inhibits gastric carcinoma cell proliferation, migration and invasion by targeting Notch1,
Activation of the Notch signaling pathway confers strong growth and motility advantage to …

GRWD1 overexpression promotes the proliferation, migration, and invasion of gastric cancer through the Notch signaling pathway

H Ding, Z Feng, K Hu - 2022 - researchsquare.com
… of Notch pathway-related proteins TACE, Notch-1/NICD1, the … expression of Notch signaling
pathway-related proteins was … TACE activity, thereby promoting Notch-1 to release NICD to …

Notch signalling pathways and their importance in the treatment of cancers

SL Teoh, S Das - Current Drug Targets, 2018 - ingentaconnect.com
… xenografted tumor growth of gastric cancer cell line throughover-expression increases
gastric cancer CSC selfrenewal ability and correlates via NOTCH1 signalling pathway activation […

A novel mechanism for C1GALT1 in the regulation of gastric cancer progression

X Dong, C Chen, X Deng, Y Liu, Q Duan, Z Peng… - Cell & Bioscience, 2021 - Springer
Gastric cancer (GC) is a highly aggressive and lethal disease around the world. High
expression of core 1 β 1, 3-galactosyltransferase 1 (C1GALT1), the primary enzyme responsible for …

[HTML][HTML] NDRG1 was downregulated and worked as favorable biomarker in the development of gastric cancer

XJ Xiao, HC Zheng - Translational Cancer Research, 2020 - ncbi.nlm.nih.gov
associated with malignant biological behavior and adverse prognosis in gastric cancer. …
As mentioned above, we conducted a GSEA to analyze NDRG1-related signal pathways in GC. …