[HTML][HTML] Regulation of the epithelial to mesenchymal transition and metastasis by Raf kinase inhibitory protein-dependent Notch1 activity

HS Noh, YS Hah, JH Ha, MY Kang, S Zada, SY Rha… - Oncotarget, 2016 - ncbi.nlm.nih.gov
… and stomach cancer is inversely correlated with endogenous levels of the Notch1 intracellular
… , resulting in suppression of the Notch signaling pathway. Interestingly, RKIP can directly …

β‑carotene reverses tobacco smoke‑induced gastric EMT via Notch pathway in vivo

L Lu, J Chen, M Li, L Tang, R Wu… - Oncology …, 2018 - spandidos-publications.com
progression of gastric cancer. Many factors are associated with the initiation and progression
of gastric … Western blot analyses of Notch-1, NICD, Hes-1 in the tissues of mice exposed to …

[HTML][HTML] The oncogenic role of Jagged1/Notch signaling in cancer

M Xiu, Y Liu, B Kuang - Biomedicine & Pharmacotherapy, 2020 - Elsevier
… 96 (75 %) gastric carcinoma (GC) patients expressed JAG1 in cancer tissues, and that this
… /Notch1 signaling pathway, and Cyclin D1 activation promotes G1 to S cell cycle progression

Mutations in the notch signalling pathway are associated with enhanced anti‐tumour immunity in colorectal cancer

F Wang, J Long, L Li, Z Zhao, F Wei… - Journal of Cellular …, 2020 - Wiley Online Library
… ), head and neck squamous cancer, gastric cancer, glioma, cervical cancer, ovarian … of
other important Notch signalling pathway-related genes besides NOTCH1, NOTCH2 and FBXW7 …

Notch signaling pathway: architecture, disease, and therapeutics

B Zhou, W Lin, Y Long, Y Yang, H Zhang… - Signal transduction and …, 2022 - nature.com
… In this review, we focus on both classical and the latest findings related to NOTCH signaling
development, related diseases, and therapeutic applications of the NOTCH pathway. The …

[HTML][HTML] Linc00641 promotes the progression of gastric carcinoma by modulating the miR-429/Notch-1 axis

Q Hang, J Lu, L Zuo, M Liu - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
progression of gastric cancer cells by targeting miR-429 and increasing the expression of
Notch-1… We concluded that targeting linc00641 may be a therapeutic strategy for gastric cancer

[HTML][HTML] SIX1 predicts poor prognosis and facilitates the progression of non-small lung cancer via activating the notch signaling pathway

S Huang, W Lin, L Wang, Y Gao, X Yuan… - … of Cancer, 2022 - ncbi.nlm.nih.gov
cancer through ZEB1 activation 36 . Zhu et al. showed that SIX1 could transcriptionally activate
the Vimentin, thereby promoting gastric cancer … induced an increase in Notch1, Notch2, …

NOTCH1 and NOTCH2 regulate epithelial cell proliferation in mouse and human gastric corpus

ES Demitrack, GB Gifford, TM Keeley… - … -Gastrointestinal …, 2017 - journals.physiology.org
… that the Notch signaling pathway is essential for proliferation … gastric adenocarcinoma cell
lines with increased NOTCH1 expression demonstrate that Notch inhibition can reduce cancer

Glutamate dehydrogenase inhibits tumor growth in gastric cancer through the Notch signaling pathway

YJ Wu, ZL Hu, SD Hu, YX Li, XW Xing… - Cancer …, 2019 - content.iospress.com
… In order to verify the functions of GDH, we trasfected GDH shRNA into gastric cancer cells
and found that GDH significantly reduced the expression of Notch1, Notch2, Notch3 and …

The self-renewal signaling pathways utilized by gastric cancer stem cells

Y Fu, H Li, X Hao - Tumor Biology, 2017 - journals.sagepub.com
… About 75% of primary gastric cancers express the Notch ligand Jag1. Activation of the Notch1
signaling pathway is associated with gastric cancer progression through COX-2. Another …