… is overexpressed in cancer stem cells. Inhibition of the Notch1 signaling pathway by using
pan-… In a study that examined the role of Notch1 in cisplatin-resistant gastric cancer cell lines …

… of NF-κB signaling pathway promotes tumor genesis which Associated with poor prognosis
of GC … of AKT can increase the binding of NF-kB on Notch1 promoter. Further up-regulation of …

… well-known oncoproteins including Notch-1 by ubiquitination-… regulates Notch1 downstream
signaling pathways through … to down-regulation of Notch1 and related pathways (Hes-1, C-…

… in gastric cancer cells and further investigated the associated … -inducible signaling pathway
protein-1 in gastric cancer, and … that Wnt1-inducible signaling pathway protein-1 expression …

… The data showed that HMGCS1 could localize into nuclei (Figure 6A,B), upregulate … in
gastric cancer cells. Thus, we believe nuclear HMGCS1 could promote gastric cancer progression …

… tumor development by regulating the expression of their target genes and downstream signaling
pathway in various types of cancer.15… Notch 1 has been found to be a major regulator of …

… regulatory pathway may be associated with the oncogene and growth of gastric cancer. In
… identified, and the regulatory pathway of circHIPK3/miR-637/AKT1 in the tumorigenesis and …

… (MAML1) and increased gastric cancer cell proliferation in vitro and tumor formation in vivo…
activation of the Notch2 signaling pathway to Notch2 methylation in gastric cancer progression…

… in tumor progression. In prostate cancer and gastric cancer, NEDD4L promotes cancer cell
… , and NEDD4L negatively regulates Notch signalling through repressing Notch1. To further …

… that many lncRNAs are associated with tumorigenesis of many cancers, such as gastric
cancer 6 , ovarian cancer 7 and EC 8 . Metastasis-associated lung adenocarcinoma transcript 1 (…