Overexpression of Pofut1 and activated Notch1 may be associated with poor prognosis in breast cancer

G Wan, L Tian, Y Yu, F Li, X Wang, C Li, S Deng… - Biochemical and …, 2017 - Elsevier
… In support of our findings, overexpresson of Pofut1 was observed in oral, gastric cancer and
hepatocellular carcinoma compared to the normal subjects [11], [15], [20]. Of which, pofut1 …

The Notch signaling pathway: a potential target for cancer immunotherapy

X Li, X Yan, Y Wang, B Kaur, H Han, J Yu - Journal of hematology & …, 2023 - Springer
… patients with gastric cancer but not in those with lung cancer [… + precursors into NK cells and
enhances the anti-tumor … ; II: Dll1 or other ligands that activate Notch1 or Notch2 increase the …

[HTML][HTML] Notch signalling pathway in development of cholangiocarcinoma

B Rauff, A Malik, YA Bhatti, SA Chudhary… - … of Gastrointestinal …, 2020 - ncbi.nlm.nih.gov
… It has been proved experimentally that miR-34a plays a significant role in suppressing the
CCA cell growth in in vivo and in vitro via Notch signalling pathway related genes Notch 1, …

Non-coding RNAs targeting notch signaling pathway in cancer: From proliferation to cancer therapy resistance

M Hashemi, S Hasani, S Hajimazdarany… - International journal of …, 2022 - Elsevier
… ), a tumor-promoting factor with high expression in gastric cancer. By activation of Notch
signaling, its … on their surface and using Notch1-antibody for delivering anti-cancer miRNAs has …

LncRNA NEAT1 promotes gastric cancer progression via miR-1294/AKT1 axis

D Wu, H Li, J Wang, H Li, Q Xiao, X Zhao, Z Huo - Open Medicine, 2020 - degruyter.com
… -kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) signaling pathway via regulating
… GC cells by regulating the PI3K/AKT/mTOR signaling pathway via the miR-1294/AKT1 axis, …

Xue-Jie-San prevents the early development of colitis-associated intestinal fibrosis by blocking Notch1 and FGL1 signaling pathways

Y Gao, LJ Lu, ZZ Zhang, X Yang, J Du, K Wen… - Journal of …, 2023 - Elsevier
… The findings of this study suggested an antagonistic effect of XJS on Notch1/Hes1/mTOR
signaling pathway. Additionally, it has been verified that FGL1 is a modulator of mTOR …

POFUT1 promotes colorectal cancer development through the activation of Notch1 signaling

Y Du, D Li, N Li, C Su, C Yang, C Lin, M Chen… - Cell death & …, 2018 - nature.com
… Besides in some solid cancers, POFUT1 activate Notch1 signaling pathway in other
pathological progress, such as to explore the effect of O-fucosylation in myogenesis, Audrey Der …

NOTCH3 as a prognostic biomarker and its correlation with immune infiltration in gastrointestinal cancers

J Xu, X Jin, H Shen, X Chen, J Chen, H Huang, B Xu… - Scientific Reports, 2024 - nature.com
… In mammals, there are four NOTCH receptors (NOTCH1-4) and five ligands [Jagged (JAG)1, …
the NOTCH3 signaling pathway and indirectly interacting with other signaling pathways

[HTML][HTML] PDGF-D promotes cell growth, aggressiveness, angiogenesis and EMT transformation of colorectal cancer by activation of Notch1/Twist1 pathway

J Chen, W Yuan, L Wu, Q Tang, Q Xia, J Ji, Z Liu… - Oncotarget, 2017 - ncbi.nlm.nih.gov
… Conversely, down-regulation of Notch1 negated the cell growth … tumor growth, aggressiveness
and angiogenesis which could be partly mediated via activating Notch1 signaling pathway

AP-2α reverses vincristine-induced multidrug resistance of SGC7901 gastric cancer cells by inhibiting the Notch pathway

W Lian, L Zhang, L Yang, W Chen - Apoptosis, 2017 - Springer
… of gastric cancer cells, which may be realized by inhibiting the Notch signaling pathway. …
of marker proteins of the Notch pathway (Cleaved Notch1 and Hes-1) and multidrug resistance …