Genome-Wide Identification and Characterization of Amino Acid Polyamine Organocation Transporter Family Genes Reveal Their Role in Fecundity Regulation in a …

L Yue, Z Guan, M Zhong, L Zhao, R Pang… - Frontiers in …, 2021 - frontiersin.org
… role by enabling the movement of amino acids into and out of insect cells. In this study, a
common amino acid transporter gene family of amino acid/polyamine/organocation (APC) was …

Fitness landscape of substrate-adaptive mutations in evolved amino acid-polyamine-organocation transporters

F Karapanagioti, ÚÁ Atlason, DJ Slotboom, B Poolman… - Elife, 2024 - elifesciences.org
… Some notable examples of gene family expansion are found within the APC (amino acid-polyamine-organocation)
superfamily of transporters, which include: the neurotransmitter …

Amino acid and polyamine membrane transporters in Trypanosoma cruzi: biological function and evaluation as drug targets

M Sayé, C Reigada, L Gauna… - Current Medicinal …, 2019 - ingentaconnect.com
… The Amino Acid-PolyamineOrganocation (APC) is one of the largest superfamilies of
transporters. A recent phylogenetic characterization of the APC superfamily identified 10 distinct …

Current status and perspectives on the role of polyamines in plant immunity

ME Gonzalez, FI Jasso‐Robles… - Annals of Applied …, 2021 - Wiley Online Library
… the L-type amino acid family of transporters (LAT), a subgroup of the amino acid-polyamine-organocation
(APC) superfamily, involved in the uptake of PAs, amino acids such as leucine …

Properties and phylogeny of 76 families of bacterial and eukaryotic organellar outer membrane pore-forming proteins

BL Reddy, MH Saier Jr - PloS one, 2016 - journals.plos.org
… Our standard methods involve the use of computer programs that use the Superfamily
Principle to determine the significance of sequence similarities [34]. The Superfamily Principle …

[PDF][PDF] Cadaverine: A diamine presence & role in plants

C Rajpal, PC Tomar - Plant Arch, 2020 - academia.edu
… The amino acid polyamine/organocation (APC) superfamily of transporters specifc for
amino acids, polyamines and organocations. Microbiology, 146: 1797-814. Jackson SA, DR …

Resculpting the binding pocket of APC superfamily LeuT-fold amino acid transporters

N Edwards, CMH Anderson, NJ Conlon… - Cellular and Molecular …, 2018 - Springer
… The largest collection of amino acid transporters (including … Amino acid-Polyamine-organoCation
(APC) superfamily. The LeuT-fold is a paradigm structure for APC superfamily amino

Molecular characterization, evolutionary and phylogenetic analyses of rice ACT/BAT-type amino acid transporters

J Saha, S Gupta - Computational Biology and Chemistry, 2022 - Elsevier
… These genes were reported to belong mainly to the ATF / AAAP family and APC family which
were again grouped under the APC superfamily. Sequence composition and phylogenetic …

Function and regulation of acid resistance antiporters

EM Krammer, M Prévost - The Journal of Membrane Biology, 2019 - Springer
… of the amino acid-polyamine-organocation (APC) superfamily of … eukaryotic amino acid
transporters of the APC superfamily as … mechanisms of amino acid recognition and translocation. …

Genome-wide identification following functional analysis of amino acid permease and cationic amino acid transporter gene families in maize and their role in drought …

MN Islam, MG Rabby, MM Hossen, M Bonny… - South African Journal of …, 2024 - Elsevier
… ), and ACT (Amino Acid/Choline Transporters) (Yang et al., 2020). The APC (Amino Acid
Polyamine Organocation) superfamily establishes the second-largest superfamily of secondary …