… Clinical practice guidelines for RLS, which are currently pharmacologically focussed, could
expand to incorporate QoL interventions and psychological implications of having RLS, as …

… The lack of a reliable biological diagnostic marker for RLS makes the clinical evaluation,
particularly collecting the patient’s medical history, a crucial step in correctly diagnosing this …

… Restless legs syndrome (RLS), the fourth leading cause of … of RLS by examining both
endogenous and exogenous factors… of drug tolerance and by the psychological management, with …

… can be conceptualized as an enhancement of a biological “drive” whose primary purpose
is … Reduction of the enhancer activity of an restless legs syndrome (RLS)–risk common …

… Thomas Willis first described RLS in 1685, which is why RLS is also commonly known as …
and named the disorder restless legs syndrome. This neurological sensorimotor disorder is …

… Currently, the prevailing theory is that brain iron deficiency is a key biological driver in RLS,
likely resulting from various factors including low peripheral iron and/or genetics [87]. RP …

… restless legs syndrome (RLS). Investigators have studied neuropathology, imaging,
electrophysiology, and genetics of RLS, identifying brain regions and biological systems affected in …

… key biological driver of RLS and may be due to various factors including low peripheral iron
levels or genetic factors. [ 27 ] Allen stated in 2015 that “the pathophysiology of RLS appears …

… movements PLMS—periodic limb movements of sleep RLSF—RLS Foundation RLS—restless
legs syndrome SIT—suggested immobilisation test sTR—soluble transferrin receptor WED…

… the management of restless leg syndrome constitute the data … used to cope with restless leg
syndrome, with full text available … Therefore, restless legs syndrome significantly affects daily …