The role of neuropeptide Y in cardiovascular health and disease

CMJ Tan, P Green, N Tapoulal… - Frontiers in …, 2018 - frontiersin.org
NPY receptors in novel therapies for cardiovascular disease. … Neuropeptide Y signaling
cascade in cardiovascular tissues … and paracrine effects of NPY modulate cardiac contractibility, …

The role of neuropeptide Y in the pathophysiology of atherosclerotic cardiovascular disease

P Zhu, W Sun, C Zhang, Z Song, S Lin - International journal of cardiology, 2016 - Elsevier
… The neuropeptide Y (NPY) has now been discovered for more than thirty … , NPY performs a
variety of physiological functions, including the regulation of food intake, cardiovascular effects

Effects of neuropeptide Y on coronary artery vasomotion in patients with microvascular angina

GMC Rosano, D Tousoulis, E McFadden… - International Journal of …, 2017 - Elsevier
Neuropeptide Y (NPY) is a potent endogenous vasoconstrictor involved in modulation of …
of neuropeptide Y (NPY) and ergonovine. Constriction of epicardial arteries in response to NPY

Neuropeptide Y is an angiogenic factor in cardiovascular regeneration

R Saraf, F Mahmood, R Amir, R Matyal - European journal of pharmacology, 2016 - Elsevier
… In this review, we will elaborate the effects of NPY and its receptors on vascular and cardiac
remodeling and outline the efforts and studies currently under way to drive its use from …

Neuropeptide Y attenuates cardiac remodeling and deterioration of function following myocardial infarction

YY Qin, XR Huang, J Zhang, W Wu, J Chen, S Wan… - Molecular Therapy, 2022 - cell.com
… Therefore, in the present study, we first characterized the NPY-producing cells in surgically
removed cardiac tissues from patients with chronic heart failure and from mice with AMI. Then…

NeuropeptideY Levels in ST‐Segment–Elevation Myocardial Infarction: Relationship With Coronary Microvascular Function, Heart Failure, and Mortality

T Gibbs, N Tapoulal, M Shanmuganathan… - Journal of the …, 2022 - Am Heart Assoc
Neuropeptide Y (NPY) is a cotransmitter that is released alongside norepinephrine from …
NPY is known to be the most abundant neuropeptide in the heart and is significantly …

Neuropeptide-Y causes coronary microvascular constriction and is associated with reduced ejection fraction following ST-elevation myocardial infarction

N Herring, N Tapoulal, M Kalla, X Ye… - European heart …, 2019 - academic.oup.com
… very high levels of NPY measured in the STEMI group where cardiac NPY release is likely to
… We also did not measure cardiac NPY release via a CS-arterial NPY difference. By the time …

Neuropeptide Y predicts cardiovascular events in chronic kidney disease patients: a cohort study

C Zoccali, G D'Arrigo, D Leonardis, P Pizzini… - Journal of …, 2019 - journals.lww.com
… of stages 2–5 CKD patients neuropeptide Y robustly predicted cardiovascular events.
Such a … On note, we registered an important effect modification by age on the NPY-cardiovascular

Coronary sinus neuropeptide Y levels and adverse outcomes in patients with stable chronic heart failure

OA Ajijola, NA Chatterjee, MJ Gonzales… - JAMA …, 2020 - jamanetwork.com
… Specifically, CS levels NPY … that cardiac release is a significant source of NPY in HF.
Therefore, in this study, we have measured CS NPY, which is more reflective of cardiac NPY

Physiological and therapeutic roles of neuropeptide Y on biological functions

P Shende, D Desai - Cell Biology and Translational Medicine, Volume 7 …, 2020 - Springer
Cardiovascular effects: NPY helps in neural regulation for functioning of cardiovascular
conditions and glucose metabolism and found in high concentrations around the blood vessels …