Single-case design, analysis, and quality assessment for intervention research

MA Lobo, M Moeyaert, AB Cunha… - Journal of neurologic …, 2017 - journals.lww.com
… A SC study should not be confused with a “case study/series” (also called “case report”). In
a typical case study/series, a single patient or small series of patients is involved, but there is …

[HTML][HTML] Making the switch: From case studies to N-of-1 trials

A Margolis, C Giuliano - Epilepsy & behavior reports, 2019 - Elsevier
… N-of-1 trials are a double-blinded randomized crossover trial within a limited number of
patients, often as small as a single patient. These trials borrow many concepts from randomized …

The single case study of memory

T Shallice - Cases of amnesia, 2019 - taylorfrancis.com
… Of all the areas of psychology, it is the area of memory, where in the last hundred years, the
description of a surprising dis order in a single patient following a neurological intervention …

[HTML][HTML] Establishment of an international collaborative network for N-of-1 trials and single-case designs

J Nikles, P Onghena, JWS Vlaeyen, RK Wicksell… - … clinical trials …, 2021 - Elsevier
… In this article we briefly examine the unique features of Single-Case Designs (SCDs) (studies
in a single participant), their history and current trends, and real-… Single patient open trials

singcar: Comparing single cases to small samples in R

J Rittmo, RD McIntosh - The Journal of Open Source Software, 2021 - research.ed.ac.uk
… naturally-occurring brain damage will be unique in each individual case. From a theoretical
perspective, this means that a single patient might be the only available source of data for a …

Expanding patient access to investigational drugs: single patient investigational new drug and the “Right to Try”

GA Van Norman - JACC: Basic to Translational Science, 2018 - jacc.org
single-patient IND requests for the same drug. An individual, or single-patient IND allows
treatment of a single patient … in the form of studies, while for a single-patient IND the physician …

Bayesian multilevel single case models using 'Stan'. A new tool to study single cases in neuropsychology

M Scandola, D Romano - Neuropsychologia, 2021 - Elsevier
… and usefulness of single case studies in current research, with … cases or the study of groups
of patients with similar conditions (Caramazza and Coltheart, 2006). Single case studies are …

[HTML][HTML] When the single matters more than the group (II): addressing the problem of high false positive rates in single case voxel based morphometry using non …

C Scarpazza, TE Nichols, D Seramondi… - Frontiers in …, 2016 - frontiersin.org
… of studies have used Voxel Based Morphometry (VBM) to compare a single patient with a …
relies on the assumption that the single patient is drawn from a hypothetical population with …

Bringing the single versus multi-patient room debate to vulnerable patient populations: a systematic review of the impact of room types on hospitalized older people …

MM Shannon, R Lipson-Smith, M Elf… - Intelligent Buildings …, 2020 - Taylor & Francis
… Importantly, apart from some signal of infection control benefits, our findings do not show
evidence to support the use of single-patient rooms with older people and people with …

Single‐case experimental designs: Characteristics, changes, and challenges

AE Kazdin - Journal of the Experimental Analysis of Behavior, 2021 - Wiley Online Library
… To begin, “single-case,” “N = 1,” “N-of-1,” and “single-patient trials” imply that only one
subject is included in an investigation. Often this is true, but it is not an inherent feature of the …