Low-dose morphine reduces tolerance to central hypovolemia in healthy adults without affecting muscle sympathetic outflow

JC Watso, LN Belval, FA Cimino 3rd… - American Journal …, 2022 - journals.physiology.org
… accelerates hemorrhage-associated hypotension in conscious sheep [intracerebroventricular …
The pharmacodynamics/pharmacokinetics of morphine and morphine metabolites result in …

Pharmacokinetics and pharmacodynamics of drugs commonly used in pregnancy and parturition

J Ansari, B Carvalho, SL Shafer… - Anesthesia & …, 2016 - ingentaconnect.com
… The peak concentration of midazolam is reduced after both oral and parenteral administration
… the exception of midazolam is close to 1 (Table 4), making midazolam the preferred drug …

Analgesic and cardiopulmonary effects of epidural romifidine and morphine combination in horses

CC Natalini, SDLA Paes, A da S Polydoro - Journal of Equine Veterinary …, 2021 - Elsevier
… different doses of romifidine combined with morphine in horses. A … 60 μg/kg (R60) combined
with morphine 0.1 mg/kg with a washout … Epidurally administered romifidine and morphine

Analgesics and sedatives in critically ill newborns and infants: the impact on long‐term neurodevelopment

RM Schiller, K Allegaert, M Hunfeld… - The Journal of …, 2018 - Wiley Online Library
… longer than its derivatives sufentanil, alfentanil, and remifentanil.In … However, associations
with morphine and midazolam … Pharmacodynamics and pharmacokinetics of morphine after …

[HTML][HTML] Integrative Cardiovascular Physiology and Pathophysiology: Low-dose morphine reduces tolerance to central hypovolemia in healthy adults without affecting …

JC Watso, LN Belval, FA Cimino 3rd… - American Journal of …, 2022 - ncbi.nlm.nih.gov
… accelerates hemorrhage-associated hypotension in conscious sheep [intracerebroventricular …
The pharmacodynamics/pharmacokinetics of morphine and morphine metabolites result in …

Analgesia during parturition in domestic animals: Perspectives and controversies on its use

D Mota-Rojas, A Velarde, M Marcet-Rius, A Orihuela… - Animals, 2022 - mdpi.com
… [4], evaluated the cumulative effect of alfentanil, meperidine, and remifentanil on strips …
pharmacokinetics of the drugs. One example of this was observed in a study of 16 gestating ewes

The minimal anaesthesia model: development and refinement of the concept and subsequent practical applications: a collection of papers and a monograph …

C Johnson - 2020 - mro.massey.ac.nz
… Potent analgesics such as alfentanil (3) appeared to reduce … consideration of cattle only to
include sheep and goats (24). … Intra-articular morphine and saline injections induce release …

Analgesia for sheep in commercial production: Where to next?

A Small, AD Fisher, C Lee, I Colditz - Animals, 2021 - mdpi.com
… research into the pharmacokinetics and efficacy of local anaesthetics in sheep was carried
… [389] evaluated the safety of lumbar intrathecal midazolam in sheep. Doses of up to 15 mg/…

What do we know about opioids and the kidney?

M Mallappallil, J Sabu, EA Friedman… - International journal of …, 2017 - mdpi.com
Pharmacokinetics of buprenorphine, alfentanil, sufentanil and remifentanil are not … to cause
harm were fentanyl, methadone and alfentanil; morphine may be associated with toxicity in …

Central nervous system penetration of the opioid oxycodone

H Kokki, M Kokki - Neuropathology of drug addictions and substance …, 2016 - Elsevier
… In sheep, the permeability of oxycodone across the BBB is … For morphine the brain
concentration was two times lower than that … Enhanced CNS pharmacokinetics and superior …