… , with characteristic peaks suitable for analytical detection. The bioavailability of these two
compounds in biological … Both alkaloids exhibit similar biological properties, although specific …

… In this study, the biotransformation in the plasma, urine and feces of rats following oral
administration of protopine (PRO) and allocryptopine (ALL)were explored using HPLC-QqTOF MS…

… a rapid, accurate and highly selective determination of protopine in rat plasma and tissues
protopine [9]. Wang et al. identified protopine from Yuanhu with the help of a comprehensive …

… Berberine, protopine and allocryptopine displayed no cytotoxic effect against L929 fibroblast
cell lines in concentration of 15.6 mg/L; lack of cytotoxicity was observed for coptisine when …

… biological characteristics of allocryptopine have been examined. Mandal et al. found that
allocryptopine … ; Liu, ZY Identification of allocryptopine and protopine metabolites in rat liver S9 …

… this plant, such as allocryptopine, O-methylflavinantin, corydine, protopine, isocorydine, …
properties. Then, for the first time, we demonstrated the inhibitory effects of allocryptopine-rich …

… , it is mentioned that protopine and allocryptopine, isolated as … inhibitory activity of protopine
and allocryptopine could be … of substrate (acetylthiocholine)–protopine was found to be a …

… This study aimed to evaluate the anti-inflammatory activity of protopine total alkaloids (… The
two main active components of MPTA, protopine and allocryptopine, were identified, and the …

… allocryptopine (5) are the most pharmacologically studied and biologically active protopines
… alkaloids are known to have diverse and significant biological properties, but so far, only 8-…

… different plant species from which protopine is isolated. Most are … documents the chemistry
and anti-AD potential of protopine. … The first chemical synthesis of protopine was performed by …