Surfactant replacement therapy: from biological basis to current clinical practice
R Hentschel, K Bohlin, A van Kaam, H Fuchs… - Pediatric …, 2020 - nature.com
… This review summarizes the current knowledge on the physiological action of endogenous
and exogenous pulmonary surfactant, the role of different types of animal-derived and …
and exogenous pulmonary surfactant, the role of different types of animal-derived and …
[HTML][HTML] A recipe for a good clinical pulmonary surfactant
J Pérez-Gil - biomedical journal, 2022 - Elsevier
… current concepts on the compositional and structural determinants defining pulmonary
surfactant … -derived or recombinant or synthetic therapeutic surfactants, as well as a the most …
surfactant … -derived or recombinant or synthetic therapeutic surfactants, as well as a the most …
Surfactants in acute respiratory distress syndrome in infants and children: past, present and future
A Amigoni, A Pettenazzo, V Stritoni, M Circelli - Clinical drug investigation, 2017 - Springer
… Natural pulmonary surfactant plays an essential role in lung physiology; it is responsible
for lowering surface tension within the alveoli and maintaining the functional integrity of the …
for lowering surface tension within the alveoli and maintaining the functional integrity of the …
Pulmonary surfactant and drug delivery: Focusing on the role of surfactant proteins
… use of (clinical) pulmonary surfactant as a drug carrier to promote drug spreading and
transport along the alveolar interface. Next, each lung surfactant protein will be introduced from a …
transport along the alveolar interface. Next, each lung surfactant protein will be introduced from a …
[HTML][HTML] Structural hallmarks of lung surfactant: Lipid-protein interactions, membrane structure and future challenges
JC Castillo-Sánchez, A Cruz, J Pérez-Gil - Archives of biochemistry and …, 2021 - Elsevier
… Lung surfactant (LS) is an outstanding example of how a highly regulated and dynamic …
stabilizes the respiratory air-liquid interface in the mammalian lung. The present review dissects …
stabilizes the respiratory air-liquid interface in the mammalian lung. The present review dissects …
Composition, Structure and Biophysical Functions of Pulmonary Surfactants: Their Deficiency and Strategy for Remedy
AK Panda - 2017 - insajournal.in
… Pulmonary surfactant (PS) is a complex mixture of lipids and proteins that forms a monomolecular
film at the lung… A brief account of the evolutionary development of pulmonary surfactant …
film at the lung… A brief account of the evolutionary development of pulmonary surfactant …
New insights into exogenous surfactant as a carrier of pulmonary therapeutics
B Baer, LMP Souza, AS Pimentel… - Biochemical …, 2019 - Elsevier
… Similarly, molecular dynamics simulations of clarithromycin interacting with a lung surfactant
model provide evidence that clarithromycin may be incorporated into the lung surfactant …
model provide evidence that clarithromycin may be incorporated into the lung surfactant …
The Lord of the Lungs: The essential role of pulmonary surfactant upon inhalation of nanoparticles
… compromise the respiratory function. This review explains the key role of pulmonary surfactant
to … with surfactant and unravelling the mutual effects. The implication of the nanoparticle-…
to … with surfactant and unravelling the mutual effects. The implication of the nanoparticle-…
Pulmonary surfactant: a mighty thin film
F Possmayer, YY Zuo, RAW Veldhuizen… - Chemical …, 2023 - ACS Publications
… pulmonary surfactant… pulmonary surfactant stabilizes our alveoli has still not been achieved.
It has long been suggested (but not always accepted) that the ability of pulmonary surfactant …
It has long been suggested (but not always accepted) that the ability of pulmonary surfactant …
Recent progress on surfactant protein A: cellular function in lung and kidney disease development
SD King, SY Chen - American Journal of Physiology-Cell …, 2020 - journals.physiology.org
… In this mini-review, we discuss SP-A functions and the consequences of SP-A genetic
mutations or pulmonary surfactant deficiencies, with a specific emphasis on the recent progress in …
mutations or pulmonary surfactant deficiencies, with a specific emphasis on the recent progress in …