… ADAMTS-4 is known to cause loss of aggrecan from articular … as a “characteristic that is
objectively measured and evaluated … The results of this study demonstrate that an ex vivo model …

… NO release was determined spectrophotometrically by measuring … iNOS, MMP-13 and
ADAMTS-4 while those derived from IFP were … instead of healthy bovine cartilage may explain the …

… larger role in cartilage differentiation in vivo and in vitro than if … tissue and characterized
using flow cytometric analysis. … increased the expression of ADAMTS-4 and -5 enzymes, …

… properties in vitro in cell models and in vivo in the mouse, … is characterized by the progressive
loss of articular cartilage … ability to regulate the activities of ADAMTS-4 and ADAMTS-5. …

… PPS stimulates proteoglycan synthesis by bovine and ovine chondrocytes … models of Ross
River virus (RRV) and CHIKV disease have been used to characterize the extent of cartilage …

… increase mRNA levels of INOS, ADAMTS-4, and MMP-13 in NP … Further histological analysis
of the cartilage revealed greater … or transduction of cells ex vivo, followed by implantation of …

… The Altmetric Attention Score is a quantitative measure of the … The degeneration of articular
cartilage in osteoarthritis (OA) … A one-way analysis of variance and posthoc Tukey’s test …

… characterized by the degeneration of articular cartilage, the … ADAMTS-4 and ADAMTS-5
are also aggrecanases that drive … established cell line are ex vivo transduced with a retrovirus …

… ODN or treatment with the activesite targeting small molecule uPA … into human cartilage
explants in the SCID RA xenograft model, … Utility of animal models for identification of potential …

… in culture for further characterisation. Retrieval and processing … -6 in a rat model of OA
reduced cartilage damage in a dose-… maintained after ex vivo expansion and can be measured, …