… from cartilage, bone, and synovium as well as characteristics … It was found that aggrecanases,
later named ADAMTS-4 and … Research with sprifermin in vitro and ex vivo has shown that …

… NO release was determined spectrophotometrically by measuring … iNOS, MMP-13 and
ADAMTS-4 while those derived from IFP were … instead of healthy bovine cartilage may explain the …

… Effects of leptin on cartilage ex vivo (II-III) ........................................… Osteoarthritis is characterized
by a gradual, progressive loss … ADAMTS-4 and ADAMTS-5 have been more recently found …

… joints [1] characterized by chronic deterioration of the articular cartilage with altered subchondral
… Experimental studies in dogs have shown inhibition of ex vivo proteoglycan synthesis …

… naturally with age and being characterized by a steep loss of … We started by assessing the
immunoregulatory capacity of … α whose presence dramatically increases ADAMTS-4/5 levels …

… in culture for further characterisation. Retrieval and processing … -6 in a rat model of OA
reduced cartilage damage in a dose-… maintained after ex vivo expansion and can be measured, …

… The Altmetric Attention Score is a quantitative measure of the … The degeneration of articular
cartilage in osteoarthritis (OA) … A one-way analysis of variance and posthoc Tukey’s test …

… ADAMTS-4 may be the primary aggrecanase in equine OA.Reactive … in an in vivo model.-
SF concentrations were highly correlated with cartilage damage in a post mortem study.…

… In contrast, ADAMTS-1 and ADAMTS-4 only cleave syndecan… full-length HS pre-treated ex
vivo with either heparinase I/III (… in vitro models of alveolar epithelial injury are characterized …

… PPS stimulates proteoglycan synthesis by bovine and ovine chondrocytes … models of Ross
River virus (RRV) and CHIKV disease have been used to characterize the extent of cartilage …