[PDF][PDF] Comparative study of the antinociceptive action of amitriptyline with fluoxetine and evaluation of their probable mechanism of this action in albino mice

P Sarma, D Phukan - International Journal of Pharmacy and …, 2018 - academia.edu
… of paroxetine (antidepressant of selective serotonin reuptake … may also play a role in
their peripheral analgesic action [30]. … , in our study, in the peripheral analgesic model, 5-HT3

Chronic Fluoxetine Impairs the Effects of 5-HT1A and 5-HT2C Receptors Activation in the PAG and Amygdala on Antinociception Induced by Aversive Situation in …

D Baptista-de-Souza, LRR Tavares… - Frontiers in …, 2020 - frontiersin.org
… Therefore, we hypothesized that chronic treatment with fluoxetine alters the role of 5-HT
1A and 5-HT 2C receptors located in the amygdaloid complex and PAG in the modulation of …

Dysfunction in serotonergic and noradrenergic systems and somatic symptoms in psychiatric disorders

Y Liu, J Zhao, X Fan, W Guo - Frontiers in psychiatry, 2019 - frontiersin.org
receptor antagonist, rather than the 5-HT2 or 5-HT3 receptorantinociceptive effects. They
microinjected yohimbine (an α2-… as fluoxetine, sertraline, paroxetine, and citalopram, SNRIs …

Monoamines as drug targets in chronic pain: focusing on neuropathic pain

L Bravo, M Llorca-Torralba, E Berrocoso… - Frontiers in …, 2019 - frontiersin.org
… Antagonism of 5-HT2 and 5-HT3 receptors is thought to dampen analgesia or potentiate the
effect of some drugs due to its role in descending facilitation pain (Ali et al., 1996; Green et al…

Phytoconstituents Targeting the Serotonin 5-HT3 Receptor: Promising Therapeutic Strategies for Neurological Disorders

L Akotkar, U Aswar, A Ganeshpurkar… - ACS Pharmacology & …, 2024 - ACS Publications
… 5-HT and its receptors play a crucial role in developing gastric … zerumbet exert their
antinociceptive effects by modulating the l-… that 5-HT1 and 5-HT2, rather than 5-HT3R, receptors

Drugs which influence serotonin transporter and serotonergic receptors: pharmacological and clinical properties in the treatment of depression

PP Taciak, N Lysenko, AP Mazurek - Pharmacological Reports, 2018 - Elsevier
… -HT 2A receptors also play considerable role in other processes. … It happened mostly with
escitalopram and paroxetine and rarely … antinociceptive effects mediated by μ1- and μ2- opioid …

Niclosamide: A Potential Antipruritic Agent by Modulating Serotonin Pathway through Metabotropic glutamate receptors.

ZE Soltani, M Elahi, MA Rad, S Farsio, AR Dehpour - Heliyon, 2024 - cell.com
… systems, while the other subtypes mostly exhibit antinociceptive functions ( … effects on the
expression of 5-HT2, mGluR1, mGluR5, and TRPV1. While there are several studies on the role

[HTML][HTML] The role of psychiatric, analgesic, and antiepileptic medications in chronic pruritus

P Patel, K Patel, K Pandher, RS Tareen - Cureus, 2021 - ncbi.nlm.nih.gov
… given 20 mg of the SSRI paroxetine once every morning for a … by the antagonism of 5-HT2
and 5-HT3 reuptake receptors. … , which have antinociceptive properties. The antihistamine …

Defensive and emotional behavior modulation by serotonin in the periaqueductal gray

P Vázquez-León, A Miranda-Páez… - Cellular and Molecular …, 2023 - Springer
… It is proposed that PAG plays an integrating role in aversive … discuss the involvement of
other receptors and brain nuclei to … to the clinical role of serotonin in various mental disorders. …

The roles of serotonin in neuropsychiatric disorders

M Pourhamzeh, FG Moravej, M Arabi… - Cellular and molecular …, 2022 - Springer
… The serotonergic system also plays roles in modulating various other ligands, including … a
wide range of biological functions, we herein first describe 5-HT’s role in the CNS, specifically …