Antihypertensive effects of peroxisome proliferator-activated receptor-β/δ activation
… atherosclerotic, anti-inflammatory and vasodilatory effects (47… /δ ligands, which produced a
strong inhibitory effect on aortic … include the upregulation of antioxidant genes, such as GPx1, …
strong inhibitory effect on aortic … include the upregulation of antioxidant genes, such as GPx1, …
Partial Synthetic PPARƳ Derivative Ameliorates Aorta Injury in Experimental Diabetic Rats Mediated by Activation of miR-126-5p Pi3k/AKT/PDK 1/mTOR Expression
… Peroxisome proliferator-activated receptor PPAR) agonists have … Streptozotocin-Induced
T2D through stimulating local … our results and confirmed the anti-inflammatory and anti-oxidant …
T2D through stimulating local … our results and confirmed the anti-inflammatory and anti-oxidant …
Diosgenin inhibits ER stress-induced inflammation in aorta via iRhom2/TACE mediated signaling in experimental diabetic rats: An in vivo and in silico approach
M Prasad, S Jayaraman, P Rajagopal… - Chemico-Biological …, 2022 - Elsevier
… It also has a strong antioxidant and anti-inflammatory … in the aorta of streptozotocin-induced
diabetic rats [15]. The … trigonelline against peroxisome proliferator-activated receptor-gamma (…
diabetic rats [15]. The … trigonelline against peroxisome proliferator-activated receptor-gamma (…
Effects of heme oxygenase system on inflammation, oxidative stress, insulin signaling and tissue injury in liver, heart, kidney and pancreas in obese, diabetic and …
M Mishra - 2017 - harvest.usask.ca
… (STAT), peroxisome proliferator-activated receptor, and cellular … expression of the anti-inflammatory
CD206 expression via … of antiinflammatory chemokine (C-X3-C motif) ligand 1 (…
CD206 expression via … of antiinflammatory chemokine (C-X3-C motif) ligand 1 (…
Targeting endothelial dysfunction and inflammation
… 4 inhibitors, peroxisome proliferator-activated receptor δ … vascular beneficial, anti-oxidative
and anti-inflammatory in either … RAS inhibitors, PPARδ ligands, GLP-1 elevators and GLP-1 …
and anti-inflammatory in either … RAS inhibitors, PPARδ ligands, GLP-1 elevators and GLP-1 …
Molecular mechanisms and therapeutic perspectives of peroxisome proliferator‐activated receptor α agonists in cardiovascular health and disease
… the ligand-activated transcription factor of a nuclear receptor … cell-tube in streptozotocin-induced
diabetic mice are absent by … -remodeling, anti-inflammatory, and antioxidative effects on …
diabetic mice are absent by … -remodeling, anti-inflammatory, and antioxidative effects on …
… restores antioxidant protection and improves myocardial insulin resistance in a rat model of metabolic syndrome and myocardial ischemia: the role of angiotensin II
L Ibarra-Lara, M Sánchez-Aguilar… - Molecules, 2016 - mdpi.com
… by peroxisome proliferator-activated receptors (PPARs). PPARs belong to the nuclear family
of ligand … in the cardioprotective effect of fenofibrate such as its anti-inflammatory effect, our …
of ligand … in the cardioprotective effect of fenofibrate such as its anti-inflammatory effect, our …
PPAR-δ: A key nuclear receptor in vascular function and remodeling
L Xiao, N Wang - Journal of Molecular and Cellular Cardiology, 2022 - Elsevier
… Peroxisome proliferator-activated receptors (PPARs) are … diabetic db/db mice [38],
streptozotocin-induced diabetic rats [39]… while enhanced the expression of anti-inflammatory …
streptozotocin-induced diabetic rats [39]… while enhanced the expression of anti-inflammatory …
Adding SGLT2 Cotransporter Inhibitor to PPARγ Activator Does Not Provide an Additive Effect in the Management of Diabetes-Induced Vascular Dysfunction
A Cinakova, P Krenek, J Klimas, E Kralova - Pharmacology, 2023 - karger.com
… that activation of peroxisome proliferator-activated receptor-gamma (… A direct anti-inflammatory
effect of dapagliflozin was … enzyme expression in streptozotocin-induced diabetic rat …
effect of dapagliflozin was … enzyme expression in streptozotocin-induced diabetic rat …
Impact of the renin–angiotensin system on the endothelium in vascular dementia: Unresolved issues and future perspectives
… memory in a streptozotocin-induced diabetes rat model [24]. … proliferator-activated receptor
α (PPARα) and PPARγ [36,37]. … other hand, holds antioxidant and anti-inflammatory effects in …
α (PPARα) and PPARγ [36,37]. … other hand, holds antioxidant and anti-inflammatory effects in …