Role of B cells in multiple sclerosis and related disorders

G Comi, A Bar‐Or, H Lassmann, A Uccelli… - Annals of …, 2021 - Wiley Online Library
… T cells are widely considered to be major contributors to inflammatory demyelination in
MS, growing evidence suggests a significant role for B cells … thought to underlie B-cell–mediated …

B cells in multiple sclerosis

M Sospedra - Current opinion in neurology, 2018 - journals.lww.com
Purpose of review Although it is becoming increasingly clear that B cells play important roles
in multiple sclerosis (MS) … The purpose of this review is to provide an overview of the current …

[HTML][HTML] Impact of B cells to the pathophysiology of multiple sclerosis

BM Arneth - Journal of Neuroinflammation, 2019 - Springer
… This review aimed to determine the role of B cells in MS development… evidence that describes
how B cells affect MS development. Articles that examined the association between B cells

B cells in multiple sclerosis

H Wekerle - Autoimmunity, 2017 - Taylor & Francis
… This review discusses nature and functions of B cells in MS, and retraces the recruitment
of brain-autoimmune B cells from the B cell repertoire. Multiple sclerosis is commonly …

[HTML][HTML] The role of B cells in multiple sclerosis: more than antibodies

MG Funaro, M Messina, M Shabbir… - Discovery …, 2016 - discoverymedicine.com
… MS, the evidence and current understanding of B cells in the … have been shown or hypothesized
to play several roles in the … evidence concerning the role of B cells in multiple sclerosis. …

[HTML][HTML] The role of B cells in primary progressive multiple sclerosis

JP Holloman, RC Axtell, NL Monson, GF Wu - Frontiers in Neurology, 2021 - frontiersin.org
… in primary progressive multiple sclerosis (PPMS) via CD20-targeted depletion implicates B
cells as … This review explores the possible mechanisms by which B cells contribute to disease …

The multiple roles of B cells in multiple sclerosis and their implications in multiple sclerosis therapies

R Li, A Bar-Or - Cold Spring Harbor perspectives …, 2019 - perspectivesinmedicine.cshlp.org
… underscores the importance of elucidating these multiple B-cell functions. In this … B cells,
migration of B cells into the central nervous system (CNS), and how different functions of B cells

[HTML][HTML] The role of B cells and antibodies in multiple sclerosis, neuromyelitis optica, and related disorders

S Häusser-Kinzel, MS Weber - Frontiers in immunology, 2019 - frontiersin.org
… summarize pro-inflammatory B cell properties in these three … on the emerging concept that
B cells or B cell subsets may exert … B cell-directed therapeutic approaches in multiple sclerosis

[HTML][HTML] Deciphering the role of B cells in multiple sclerosis—towards specific targeting of pathogenic function

K Lehmann-Horn, S Kinzel, MS Weber - International journal of molecular …, 2017 - mdpi.com
… regulatory functions of B cells in MS … role of B cells, plasma cells and antibodies in the
development and progression of MS. Within this first section, we will describe how activated B cells

Contribution of B cells to cortical damage in multiple sclerosis

P Bhargava, HP Hartung, PA Calabresi - Brain, 2022 - academic.oup.com
… in progressive multiple sclerosis, has led to novel hypotheses regarding the role of B cells
in mediating cortical pathology. In this paper, we describe the emerging role of B cells in …